Gene Symbol | Inhba |
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Entrez Gene | 16323 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | inhibin beta-A |
Other Description | activin beta-A chain|inhibin beta A chain |
Swissprots | Q04998 |
Accessions | BAA92352 EDL32727 Q04998 AK134991 BAE22374 AK135474 BAE22545 BC053527 AAH53527 CT010380 CAJ18587 X69619 CAA49325 XM_006516558 XP_006516621 XM_006516559 XP_006516622 XM_011244285 XP_011242587 XM_011244286 XP_011242588 NM_008380 NP_032406 |
Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
Subcellular Location | Secreted. |
Tissue Specificity | Uterus, ovary and liver. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Inhibin β-A siRNA (m) - sc-39784 from Santa Cruz Biotechnology
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Inhibin β-A shRNA Plasmid (m) - sc-39784-SH from Santa Cruz Biotechnology
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Inhibin β-A shRNA (m) Lentiviral Particles - sc-39784-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU017441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33844 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33844 from Sigma-Aldrich
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INHBA siRNA (Mouse) - CRM2083 from Cohesion Biosciences
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INHBA - MBS8241152 from MyBioSource
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shRNA set against Mouse INHBA (NM_008380.1) - SHH319545 from Creative biogene
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shRNA set against Mouse Inhba(NM_008380.1) - SHL178272 from Creative biogene
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INHBA shRNA Plasmid (Mouse) - CHM2083 from Cohesion Biosciences
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INHBA miRNA 3'UTR clone - MiUTR1M-06051 from Creative biogene
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