Gene Symbol | FANCE |
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Entrez Gene | 2178 |
Alt Symbol | FACE, FAE |
Species | Human |
Gene Type | protein-coding |
Description | Fanconi anemia, complementation group E |
Other Description | Fanconi anemia group E protein |
Swissprots | Q9HB96 Q4ZGH2 A8K907 |
Accessions | AAY26395 EAX03830 Q9HB96 AF265210 AAG16743 AK292522 BAF85211 AK312617 BC046359 AAH46359 XM_005248885 XP_005248942 XM_005248886 XP_005248943 XM_005248887 XP_005248944 XM_005248888 XP_005248945 XM_011514343 XP_011512645 XM_011514344 XP_011512646 NM_021922 NP_068741 |
Function | As part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. Required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2. {ECO:0000269|PubMed:12093742, ECO:0000269|PubMed:17296736}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12093742, ECO:0000269|PubMed:17296736}. |
Top Pathways | Fanconi anemia pathway |
FANCE CRISPR/Cas9 KO Plasmid (h) - sc-409176 from Santa Cruz Biotechnology
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FANCE HDR Plasmid (h) - sc-409176-HDR from Santa Cruz Biotechnology
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FANCE Double Nickase Plasmid (h) - sc-409176-NIC from Santa Cruz Biotechnology
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FANCE Double Nickase Plasmid (h2) - sc-409176-NIC-2 from Santa Cruz Biotechnology
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FANCE CRISPR Activation Plasmid (h) - sc-409176-ACT from Santa Cruz Biotechnology
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FANCE CRISPR Activation Plasmid (h2) - sc-409176-ACT-2 from Santa Cruz Biotechnology
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FANCE Lentiviral Activation Particles (h) - sc-409176-LAC from Santa Cruz Biotechnology
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FANCE Lentiviral Activation Particles (h2) - sc-409176-LAC-2 from Santa Cruz Biotechnology
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FANCE siRNA (h) - sc-40569 from Santa Cruz Biotechnology
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FANCE shRNA Plasmid (h) - sc-40569-SH from Santa Cruz Biotechnology
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FANCE shRNA (h) Lentiviral Particles - sc-40569-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU049561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2481 from Sigma-Aldrich
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FANCE siRNA (Human) - CRH1517 from Cohesion Biosciences
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FANCE - MBS8237978 from MyBioSource
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shRNA set against Human FANCE (NM_021922.2) - SHH292301 from Creative biogene
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Human FANCE siRNA - orb262019 from Biorbyt
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FANCE shRNA Plasmid (Human) - CHH1517 from Cohesion Biosciences
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FANCE miRNA 3'UTR clone - MiUTR1H-03508 from Creative biogene
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