| Gene Symbol |
CAPG
|
| Entrez Gene |
822
|
| Alt Symbol |
AFCP, HEL-S-66, MCP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
capping protein (actin filament), gelsolin-like
|
| Other Description |
actin regulatory protein CAP-G|actin-regulatory protein CAP-G|epididymis secretory protein Li 66|gelsolin-like capping protein|macrophage capping protein|macrophage-capping protein
|
| Swissprots |
D6W5K8 B8ZZS7 Q53SA7 P40121
|
| Accessions |
AAA92670 AAY24128 EAW99517 EAW99518 EAW99519 EAW99520 P40121 AK130130 AK225374 AK225378 AK300507 BAG62220 AK309290 AK313898 BAG36621 AU099216 BC000728 AAH00728 BC014549 AAH14549 BU626913 DQ892163 ABM83089 DQ895357 ABM86283 FJ224312 ACI46004 M94345 AAA59570 XM_005264581 XP_005264638 XM_011533122 XP_011531424 XM_011533123 XP_011531425 NM_001256139 NP_001243068 NM_001256140 NP_001243069 NM_001747 NP_001738
|
| Function |
Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17081065}. Nucleus {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
|
| Tissue Specificity |
Macrophages and macrophage-like cells.
|
![Western Blot: Actin Regulatory Protein Overexpression Lysate (Adult Normal) [NBL1-08676] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Actin Regulatory Protein.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/9444_Actin%2520Regulatory%2520Protein%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-08676-img0002.jpg)