Gene Symbol | DCHS1 |
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Entrez Gene | 8642 |
Alt Symbol | CDH19, CDH25, CDHR6, FIB1, PCDH16, VMLDS1 |
Species | Human |
Gene Type | protein-coding |
Description | dachsous cadherin-related 1 |
Other Description | cadherin-19|cadherin-25|cadherin-related family member 6|fibroblast cadherin 1|fibroblast cadherin FIB1|protein dachsous homolog 1|protocadherin-16 |
Swissprots | Q96JQ0 O15098 |
Accessions | EAW68683 Q96JQ0 AB000895 BAA21133 AB053446 BAB61903 AI767189 AK021852 BAB13913 AL831828 CAD38541 BC038382 NM_003737 NP_003728 NM_024542 |
Function | Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=In the embryonic cortex, FAT4 and DCHS1 accumulated at the cell-cell boundaries located apical to the adherens junction. {ECO:0000250}. |
Tissue Specificity | Expressed in fibroblasts but not in melanocytes or keratinocytes. {ECO:0000269|PubMed:9199196}. |
DCHS1 CRISPR/Cas9 KO Plasmid (h) - sc-408790 from Santa Cruz Biotechnology
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DCHS1 HDR Plasmid (h) - sc-408790-HDR from Santa Cruz Biotechnology
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DCHS1 Double Nickase Plasmid (h) - sc-408790-NIC from Santa Cruz Biotechnology
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DCHS1 Double Nickase Plasmid (h2) - sc-408790-NIC-2 from Santa Cruz Biotechnology
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DCHS1 CRISPR Activation Plasmid (h) - sc-408790-ACT from Santa Cruz Biotechnology
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DCHS1 CRISPR Activation Plasmid (h2) - sc-408790-ACT-2 from Santa Cruz Biotechnology
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DCHS1 Lentiviral Activation Particles (h) - sc-408790-LAC from Santa Cruz Biotechnology
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DCHS1 Lentiviral Activation Particles (h2) - sc-408790-LAC-2 from Santa Cruz Biotechnology
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DCHS1 siRNA (h) - sc-96462 from Santa Cruz Biotechnology
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DCHS1 shRNA Plasmid (h) - sc-96462-SH from Santa Cruz Biotechnology
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DCHS1 shRNA (h) Lentiviral Particles - sc-96462-V from Santa Cruz Biotechnology
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DCHS1 RNAi - H00008642-R01 from Novus Biologicals
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Cadherin-19 RNAi - H00028513-R01 from Novus Biologicals
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MISSION® esiRNA - EHU053431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6984 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6984 from Sigma-Aldrich
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DCHS1 siRNA (Human) - CRH5680 from Cohesion Biosciences
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DCHS1 - MBS8206621 from MyBioSource
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shRNA set against Human DCHS1 (NM_003737.2) - SHH275137 from Creative biogene
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Human DCHS1 siRNA - orb266182 from Biorbyt
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DCHS1 shRNA Plasmid (Human) - CHH5680 from Cohesion Biosciences
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DCHS1 miRNA 3'UTR clone - MiUTR1H-02687 from Creative biogene
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