MGME1

Gene Symbol MGME1
Entrez Gene 92667
Alt Symbol C20orf72, DDK1, MTDPS11, bA504H3.4
Species Human
Gene Type protein-coding
Description mitochondrial genome maintenance exonuclease 1
Other Description -
Swissprots B2RDG5 Q96SW3 Q9BQP7 D3DW29
Accessions EAX10260 EAX10261 EAX10262 Q9BQP7 AF306684 AF306685 AF306686 AK027503 BAB55160 AK309563 AK309995 AK310282 AK315532 BAG37912 BC016869 AAH16869 HQ447812 ADQ32296 XM_005260866 XP_005260923 XM_005260867 XP_005260924 XM_005260870 XP_005260927 XM_006723663 XP_006723726 XM_011529394 XP_011527696 XM_011529395 XP_011527697 NM_052865 NP_443097
Function Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells. {ECO:0000255|HAMAP- Rule:MF_03030, ECO:0000269|PubMed:23313956, ECO:0000269|PubMed:23358826}.
Subcellular Location Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03030, ECO:0000269|PubMed:23313956, ECO:0000269|PubMed:23358826}.

C20orf72 (K-20) - sc-85434 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

C20orf72 (P-20) - sc-85435 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-c20orf72 antibody - ab95093 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-c20orf72 antibody (ab95093) at 1/100 dilution + CEM cell lysate at 35 µg

Anti-MGME1 / C20orf72 Antibody (C-Terminus) - LS-C170659 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

C20orf72 Antibody - NBP1-91726 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15115R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15115R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15115R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15115R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, Cy3 Conjugated - bs-15115R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, Cy5 Conjugated - bs-15115R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, Cy5.5 Conjugated - bs-15115R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, Cy7 Conjugated - bs-15115R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, FITC Conjugated - bs-15115R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, Biotin Conjugated - bs-15115R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody, HRP Conjugated - bs-15115R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-C20orf72 (81-95) antibody produced in rabbit - SAB1102591 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human C20orf72 was separated on SDS-PAGE, blotted with Anti-C20orf72 (81-95) (<B>Cat. No. SAB1102591</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + C20orf72 immunizing peptide (human, 81-95)

Anti-MGME1 antibody produced in rabbit - HPA040913 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-C20orf72: <B>Cat. No. HPA040913</B>: Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.

Anti-C20orf72 (101-115) antibody produced in rabbit - SAB1102592 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human C20orf72 was separated on SDS-PAGE, blotted with Anti-C20orf72 (101-115) (<B>Cat. No. SAB1102592</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + C20orf72 immunizing peptide (human, 101-115)

C20orf72 Antibody - C-terminal region (ARP69139_P050) - ARP69139_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C20orf72 antibody [N2C3] - GTX120418 from GeneTex

Host Rabbit
Clonality Polyclonal

c20orf72 Polyclonal Antibody - bs-15115R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C20orf72 antibody - 23178-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human liver cancer slide using 23178-1-AP( MGME1 Antibody) at dilution of 1:50 (under 10x lens)

MGME1 antibody - 23178-1-AP from Proteintech Group

Prices $279.00
Sizes con: 69 μg/150μl
Host Rabbit
Clonality Polyclonal
Jurkat cells were subjected to SDS PAGE followed by western blot with 23178-1-AP(MGME1 antibody) at dilution of 1:1000

C20orf72, Polyclonal Antibody - MBS2516969 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal
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