| Gene Symbol |
ATF5
|
| Entrez Gene |
22809
|
| Alt Symbol |
ATFX, HMFN0395
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
activating transcription factor 5
|
| Other Description |
cAMP-dependent transcription factor ATF-5|cyclic AMP-dependent transcription factor ATF-5|transcription factor ATFx
|
| Swissprots |
Q9UNQ3 Q9Y2D1 B3KND3 Q9BSA1
|
| Accessions |
CAC34908 CAE92201 EAW52581 EAW52582 EAW52583 Q9Y2D1 AB021663 BAA78477 AB073613 BAD38650 AF101388 AAD28370 AF305687 AAG22558 AK024402 BAG51295 AK091985 AK290592 BAF83281 BC005174 AAH05174 BF528888 BM462249 BP378116 BU187153 BU730542 DA251296 DA684664 HY011917 XM_011526629 XP_011524931 NM_001193646 NP_001180575 NM_001290746 NP_001277675 NM_012068 NP_036200
|
| Function |
Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4. {ECO:0000269|PubMed:10373550, ECO:0000269|PubMed:15358120}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15358120}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:15358120}.
|
![Western Blot: ATF5 Overexpression Lysate (Adult Normal) [NBL1-07792] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ATF5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9208_ATF5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07792-img0002.jpg)