UGT2B4

Gene Symbol	UGT2B4
Entrez Gene	7363
Alt Symbol	HLUG25, UDPGT2B4, UDPGTH1, UDPGTh-1, UGT2B11
Species	Human
Gene Type	protein-coding
Description	UDP glucuronosyltransferase 2 family, polypeptide B4
Other Description	UDP-glucuronosyltransferase 2B4|UDP-glucuronyltransferase, family 2, beta-4|UDPGT 2B4|hyodeoxycholic acid|hyodeoxycholic acid-specific UDPGT
Swissprots	A6NCP7 G5E9X8 O60867 Q1HBF9 P06133 O75614 O60731 Q6QQX7 P36538 B4DT75
Accessions	AAF78145 ABF47107 EAX05591 EAX05592 P06133 AF064200 AAC95002 AF081793 AAC32272 AJ005162 CAA06396 AK292748 BAF85437 AK300084 BAG61887 AY529122 AAS47487 BC026264 AAH26264 BX494777 DB185148 DQ895203 ABM86129 Y00317 CAA68415 XM_005265701 XP_005265758 NM_001297615 NP_001284544 NM_001297616 NP_001284545 NM_021139 NP_066962
Function	UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4- nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Subcellular Location	Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Top Pathways	Chemical carcinogenesis, Bile secretion, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UGT2B4 protein fragment - ab159778 from Abcam Category Protein Source Wheat germ Species Human

UGT2B11 Antibody Blocking Peptide - LS-E2485 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

UGT2B4 Antibody Blocking Peptide - LS-E17908 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human UGT2B4 Protein - H00007363-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

UGT2B4 Blocking Peptide - 33R-6722 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

UGT2B4 / UGT2B11 - H00007363-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

UGT2B4 / UGT2B11 - H00007363-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

UGT2B4 fusion protein - ag2579 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

UGT2B4 fusion protein - Ag8058 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human UDP-glucuronosyltransferase 2B4(UGT2B4) - CSB-YP025597HU CSB-EP025597HU CSB-BP025597HU CSB-MP025597HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

UGT2B4-Blocking-PeptideN-term - BP19747a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UGT2B4-Blocking-Peptide-C-term - BP21489b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UGT2B4-Blocking-Peptide-Center - BP21593c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

UGT2B11 Peptide, Human - M34GP17058H from Creative Peptides Category Peptide Source Synthetic. Species Human

UGT2B4 Peptide, Human - M34GP17062H from Creative Peptides Category Peptide Source Synthetic. Species Human

UGT2B4 Recombinant Protein Antigen - NBP2-54718PEP from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µl Source E.coli Species Human

Search more