CASP4

Gene Symbol	CASP4
Entrez Gene	837
Alt Symbol	ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX
Species	Human
Gene Type	protein-coding
Description	caspase 4, apoptosis-related cysteine peptidase
Other Description	CASP-4|ICE(rel)-II|apoptotic cysteine protease Mih1/TX|caspase 4, apoptosis-related cysteine protease|caspase-4|protease ICH-2|protease TX
Swissprots	A2NHL8 A2NHM0 P49662
Accessions	ABR09278 CAA03154 EAW67050 EAW67051 EAW67052 EAW67053 P49662 AI128358 AK057094 BAG51861 AK225751 AK296081 BAG58837 AK304222 BAG65094 AL050391 CAB43686 BC008060 BC017839 AAH17839 CN261701 DQ891983 ABM82909 DQ895173 ABM86099 U25804 AAA86890 U28014 AAA75171 U28976 AAC99850 U28977 AAC99851 U28978 AAC99852 U28979 AAC99853 Z48810 CAA88750 XM_011543019 XP_011541321 NM_001225 NP_001216 NM_033306 NP_150649 NM_033307
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. Involved in ER-stress induced apoptosis. Cleaves caspase-1. {ECO:0000269|PubMed:15123740, ECO:0000269|Ref.14}.
Subcellular Location	Endoplasmic reticulum membrane. Mitochondrion.
Tissue Specificity	Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

caspase-4 p20 CRISPR/Cas9 KO Plasmid (h) - sc-400858 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

caspase-4 p20 HDR Plasmid (h) - sc-400858-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

caspase-4 p20 Double Nickase Plasmid (h) - sc-400858-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

caspase-4 p20 Double Nickase Plasmid (h2) - sc-400858-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

caspase-4 p20 CRISPR Activation Plasmid (h) - sc-400858-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

caspase-4 p20 CRISPR Activation Plasmid (h2) - sc-400858-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

caspase-4 p20 Lentiviral Activation Particles (h) - sc-400858-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

caspase-4 p20 Lentiviral Activation Particles (h2) - sc-400858-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

caspase-4/5 p10 siRNA (h) - sc-43668 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

caspase-4/5 p10 shRNA Plasmid (h) - sc-43668-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

caspase-4/5 p10 shRNA (h) Lentiviral Particles - sc-43668-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

caspase-4 siRNA (h) - sc-72798 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

caspase-4 shRNA Plasmid (h) - sc-72798-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

caspase-4 shRNA (h) Lentiviral Particles - sc-72798-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU156131 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® esiRNA - EHU103591 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5385 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5385 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00082 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr00082

CASP4 siRNA (Human) - CRH0591 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CASP4 - MBS8206264 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CASP4 (NM_001225.3) - SHH254985 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CASP4(NM_033306.2) - SHG142567 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human CASP4(NM_001225.3) - SHG142649 from Creative biogene Category siRNA Species Reactivities Human

Human CASP4 siRNA - orb261093 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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