APLN

Gene Symbol	APLN
Entrez Gene	8862
Alt Symbol	APEL, XNPEP2
Species	Human
Gene Type	protein-coding
Description	apelin
Other Description	AGTRL1 ligand|APJ endogenous ligand
Swissprots	Q8WU89 Q9ULZ1 Q4VY08
Accessions	AAF25815 EAX11828 EAX11829 Q9ULZ1 AB023493 BAA84975 AF086248 AK001855 AK312061 BAG34997 AY358657 AAQ89020 BC021104 AAH21104 BM992527 DB481574 DQ892125 ABM83051 DQ895318 ABM86244 NM_017413 NP_059109
Function	Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior. {ECO:0000269|PubMed:11090199}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat Apelin ELISA Kit (Competitive EIA) - LS-F2 from LifeSpan Bioscience Category ELISA Kit Prices $440.00, $820.00, $1,900.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.1 ng/ml Range 0.1-1000 ng/ml

Human Apelin ELISA Kit (Competitive EIA) - LS-F8243 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 19.75 pg/ml Range 0.1-1000 ng/ml

Mouse Apelin ELISA Kit (Competitive EIA) - LS-F9060 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 35.3 pg/ml Range 0.1-1000 ng/ml

Rat Apelin ELISA Kit (Competitive EIA) - LS-F8990 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 12.35 pg/ml Range 0.1-1000 ng/ml

Human Apelin 36 ELISA Kit (Sandwich ELISA) - LS-F10850 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 62.5 Range 62.5-4000 pg/ml

Rat Apelin ELISA Kit (Sandwich ELISA) - LS-F10851 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 31.2 Range 0.1-1000 ng/ml

Apelin EIA Kit - RAB0018 from Sigma-Aldrich Prices $414.00 Sizes 1 kt

Human Apelin ELISA Kit - abx150696 from Abbexa Category ELISA Kit Sensitivity 38.25 pg/ml Range 98.77 pg/ml - 8000 pg/ml

Human Apelin ELISA Kit - abx051315 from Abbexa Category ELISA Kit Sensitivity 16 pg/ml Range 35 pg/ml - 1600 pg/ml

Apelin (APLN), Human, ELISA Kit - CED066Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 6.13pg/mL Range 12.35-1,000pg/mL

Apelin, APLN, Human, ELISA Kit - E2232h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 62.5-4000 pg/mL

Apelin, Human, ELISA Kit - CSB-E14334h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 31.25 pg/ml Range 125 pg/ml-8000 pg/ml

Apelin, Human, ELISA Kit - E01A1592 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Apelin, APLN, Human, ELISA Kit - E-EL-H0456 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Apelin, APLN, Rabbit, ELISA Kit - E-EL-RB1580 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Apelin, APLN, Chicken, ELISA Kit - E-EL-Ch1680 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Apelin, APLN, Porcine, ELISA Kit - E-EL-P1795 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Apelin, APLN, Sheep, ELISA Kit - E-EL-S0312 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Apelin, APLN, Monkey, ELISA Kit - E-EL-MK0636 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

APLN (Human) Matched Antibody Pair - H00008862-AP41 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

APLN (Human) Matched Antibody Pair - H00008862-AP42 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

APLN (Human) Matched Antibody Pair - H00008862-AP43 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

APLN (Human) Matched Antibody Pair - H00008862-AP44 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

APLN (Human) Matched Antibody Pair - H00008862-AP45 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

APLN (Human) Matched Antibody Pair - H00008862-AP46 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

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