Gene Symbol | Pla2g10 |
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Entrez Gene | 26565 |
Alt Symbol | PLA2GX, mGXsPLA2, sPLA2-X |
Species | Mouse |
Gene Type | protein-coding |
Description | phospholipase A2, group X |
Other Description | GX sPLA2|group 10 secretory phospholipase A2|group X secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 10 |
Swissprots | Q9EQK6 Q9QXX3 |
Accessions | EDK97369 EDK97370 Q9QXX3 AF166097 AAF04498 AF210429 AAG43522 AK076921 BAC36530 AV075661 BC028879 AAH28879 CJ047253 KC789644 AGO86070 NM_001291009 NP_001277938 NM_011987 NP_036117 NR_110990 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in various tissues including the lung, thymus, and spleen. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
group X sPLA 2 CRISPR/Cas9 KO Plasmid (m) - sc-424101 from Santa Cruz Biotechnology
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group X sPLA 2 HDR Plasmid (m) - sc-424101-HDR from Santa Cruz Biotechnology
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group X sPLA 2 Double Nickase Plasmid (m) - sc-424101-NIC from Santa Cruz Biotechnology
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group X sPLA 2 Double Nickase Plasmid (m2) - sc-424101-NIC-2 from Santa Cruz Biotechnology
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group X sPLA 2 CRISPR Activation Plasmid (m) - sc-424101-ACT from Santa Cruz Biotechnology
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group X sPLA 2 CRISPR Activation Plasmid (m2) - sc-424101-ACT-2 from Santa Cruz Biotechnology
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group X sPLA 2 Lentiviral Activation Particles (m) - sc-424101-LAC from Santa Cruz Biotechnology
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group X sPLA 2 Lentiviral Activation Particles (m2) - sc-424101-LAC-2 from Santa Cruz Biotechnology
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group X sPLA 2 siRNA (m) - sc-60031 from Santa Cruz Biotechnology
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group X sPLA 2 shRNA Plasmid (m) - sc-60031-SH from Santa Cruz Biotechnology
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group X sPLA 2 shRNA (m) Lentiviral Particles - sc-60031-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU032111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN38812 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38812 from Sigma-Aldrich
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PLA2G10 siRNA (Mouse) - CRM4775 from Cohesion Biosciences
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shRNA set against Mouse PLA2G10 (NM_011987.2) - SHH376668 from Creative biogene
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shRNA set against Mouse Pla2g10(NM_011987.2) - SHR118722 from Creative biogene
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PLA2G10 shRNA Plasmid (Mouse) - CHM4775 from Cohesion Biosciences
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PLA2G10 miRNA 3'UTR clone - MiUTR1M-09277 from Creative biogene
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