| Gene Symbol |
Trpc4
|
| Entrez Gene |
84494
|
| Alt Symbol |
Trp4, Trrp4
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
transient receptor potential cation channel, subfamily C, member 4
|
| Other Description |
CCE1|capacitative calcium entry channel 1|short transient receptor potential channel 4|transient receptor potential channel 4|transient receptor potential protein 4
|
| Swissprots |
O35119 Q9EQ74 Q9EQ75
|
| Accessions |
EDM14938 EDM14939 EDM14940 EDM14941 O35119 AB008889 BAA23599 AF288407 AAG21809 AF288408 AAG21810 AF421363 AAL24554 AF421364 AAL24555 AF421365 AAL24556 AF421366 AAL24557 AF421367 AAL24558 AF421368 AAL24559 FQ228645 XM_006232356 XP_006232418 XM_008761008 XP_008759230 NM_001083115 NP_001076584 NM_080396 NP_536321 NM_053434
|
| Function |
Thought to form non-selective a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Acts as a cell- cell contact-dependent endothelial calcium entry channel. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|