Gene Symbol | TRMT10C |
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Entrez Gene | 54931 |
Alt Symbol | HNYA, MRPP1, RG9MTD1 |
Species | Human |
Gene Type | protein-coding |
Description | tRNA methyltransferase 10 homolog C (S. cerevisiae) |
Other Description | HBV pre-S2 trans-regulated protein 2|RNA (guanine-9-) methyltransferase domain containing 1|mitochondrial RNase P subunit 1|mitochondrial ribonuclease P protein 1|renal carcinoma antigen NY-REN-49 |
Swissprots | Q9NX54 Q7L0Y3 Q9Y596 Q9NRG5 |
Accessions | EAW79795 Q7L0Y3 AF086243 AF155111 AAD42877 AF226052 AAF86952 AK000439 BAA91166 AK026532 AY561707 AAS66980 BC035967 AAH35967 BM752893 BU619586 HQ447662 ADQ32147 NM_017819 NP_060289 |
Function | Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. {ECO:0000269|PubMed:18984158, ECO:0000269|PubMed:21593607}. |
Subcellular Location | Mitochondrion matrix, mitochondrion nucleoid {ECO:0000269|PubMed:18984158, ECO:0000269|PubMed:23473034}. |
RG9MTD1 CRISPR/Cas9 KO Plasmid (h) - sc-418590 from Santa Cruz Biotechnology
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RG9MTD1 HDR Plasmid (h) - sc-418590-HDR from Santa Cruz Biotechnology
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RG9MTD1 Double Nickase Plasmid (h) - sc-418590-NIC from Santa Cruz Biotechnology
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RG9MTD1 Double Nickase Plasmid (h2) - sc-418590-NIC-2 from Santa Cruz Biotechnology
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RG9MTD1 CRISPR Activation Plasmid (h) - sc-418590-ACT from Santa Cruz Biotechnology
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RG9MTD1 CRISPR Activation Plasmid (h2) - sc-418590-ACT-2 from Santa Cruz Biotechnology
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RG9MTD1 Lentiviral Activation Particles (h) - sc-418590-LAC from Santa Cruz Biotechnology
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RG9MTD1 Lentiviral Activation Particles (h2) - sc-418590-LAC-2 from Santa Cruz Biotechnology
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RG9MTD1 siRNA (h) - sc-78547 from Santa Cruz Biotechnology
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RG9MTD1 shRNA Plasmid (h) - sc-78547-SH from Santa Cruz Biotechnology
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RG9MTD1 shRNA (h) Lentiviral Particles - sc-78547-V from Santa Cruz Biotechnology
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RG9MTD1 RNAi - H00054931-R01 from Novus Biologicals
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MISSION® esiRNA - EHU032961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18194 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18194 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01793 from Sigma-Aldrich
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TRMT10C siRNA (Human) - CRJ0334 from Cohesion Biosciences
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TRMT10C - MBS8207493 from MyBioSource
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shRNA set against Human RG9MTD1 (NM_017819.2) - SHH392504 from Creative biogene
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shRNA set against Human RG9MTD1(NM_017819.2) - SHR170068 from Creative biogene
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Human TRMT10C siRNA - orb270835 from Biorbyt
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TRMT10C shRNA Plasmid (Human) - CHJ0334 from Cohesion Biosciences
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TRMT10C miRNA 3'UTR clone - MiUTR1H-08768 from Creative biogene
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