Gene Symbol | KRT6A |
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Entrez Gene | 3853 |
Alt Symbol | CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D, PC3 |
Species | Human |
Gene Type | protein-coding |
Description | keratin 6A, type II |
Other Description | KDAMP|cytokeratin 6A|cytokeratin 6C|cytokeratin 6D|kamp-keratin derived antimicrobial peptide|keratin 6A, , type II|keratin, epidermal type II, K6A|keratin, type II cytoskeletal 6A|type-II keratin Kb6 |
Swissprots | Q96CL4 Q08AR4 P48667 Q6NT67 P02538 A4QPC1 |
Accessions | AAC41767 AAC41769 CAA24760 EAW96631 P02538 AK290245 BAF82934 AK299386 BAG61372 AK299428 BAG61408 AK301686 BAG63158 BC008807 AAH08807 BC014152 AAH14152 BC069269 AAH69269 BC125058 AAI25059 BC139753 AAI39754 BG059253 BT006899 AAP35545 BT007605 AAP36273 DA451441 DQ890619 ABM92236 DQ893788 ABM84714 NM_005554 NP_005545 |
Function | Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. {ECO:0000250|UniProtKB:P50446}. |
Tissue Specificity | Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath. |
Cytokeratin 6A CRISPR/Cas9 KO Plasmid (h) - sc-401650 from Santa Cruz Biotechnology
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Cytokeratin 6A HDR Plasmid (h) - sc-401650-HDR from Santa Cruz Biotechnology
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Cytokeratin 6A Double Nickase Plasmid (h) - sc-401650-NIC from Santa Cruz Biotechnology
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Cytokeratin 6A Double Nickase Plasmid (h2) - sc-401650-NIC-2 from Santa Cruz Biotechnology
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Cytokeratin 6A CRISPR Activation Plasmid (h) - sc-401650-ACT from Santa Cruz Biotechnology
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Cytokeratin 6A CRISPR Activation Plasmid (h2) - sc-401650-ACT-2 from Santa Cruz Biotechnology
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Cytokeratin 6A Lentiviral Activation Particles (h) - sc-401650-LAC from Santa Cruz Biotechnology
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Cytokeratin 6A Lentiviral Activation Particles (h2) - sc-401650-LAC-2 from Santa Cruz Biotechnology
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Cytokeratin 6A siRNA (h) - sc-105266 from Santa Cruz Biotechnology
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Cytokeratin 6A shRNA Plasmid (h) - sc-105266-SH from Santa Cruz Biotechnology
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Cytokeratin 6A shRNA (h) Lentiviral Particles - sc-105266-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11392 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11392 from Sigma-Aldrich
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KRT6A siRNA (Human) - CRH2613 from Cohesion Biosciences
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Cytokeratin 6A CRISPR/Cas9 KO Plasmid (h2) - sc-401650-KO-2 from Santa Cruz Biotechnology
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Cytokeratin 6A HDR Plasmid (h2) - sc-401650-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human KRT6A (NM_005554.3) - SHH327595 from Creative biogene
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shRNA set against Human KRT6A(NM_005554.3) - SHL198918 from Creative biogene
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Human KRT6A siRNA - orb263115 from Biorbyt
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KRT6A shRNA Plasmid (Human) - CHH2613 from Cohesion Biosciences
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KRT6A miRNA 3'UTR clone - MiUTR1H-05460 from Creative biogene
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