Gene Symbol | VLDLR |
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Entrez Gene | 7436 |
Alt Symbol | CAMRQ1, CARMQ1, CHRMQ1, VLDLRCH |
Species | Human |
Gene Type | protein-coding |
Description | very low density lipoprotein receptor |
Other Description | VLDL receptor|VLDL-R|very low-density lipoprotein receptor |
Swissprots | B2RMZ7 P98155 Q5VVF6 D3DRH6 |
Accessions | AAY46157 BAA03969 EAW58804 EAW58805 EAW58806 EAW58807 EAW58808 P98155 AA758887 AB208822 BAD92059 AK092381 BAC03874 AK095744 BAG53118 AK289527 BAF82216 BC136562 AAI36563 BC142653 AAI42654 BC144245 AAI44246 D16493 BAA03945 D16494 BAA03946 L20470 AAA53684 L22431 AAA61344 S73849 AAB31735 XM_011518029 XP_011516331 NM_001018056 NP_001018066 NM_003383 NP_003374 |
Function | Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein. |
Tissue Specificity | Abundant in heart and skeletal muscle; also ovary and kidney; not in liver. |
VLDLR CRISPR/Cas9 KO Plasmid (h) - sc-401310 from Santa Cruz Biotechnology
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VLDLR HDR Plasmid (h) - sc-401310-HDR from Santa Cruz Biotechnology
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VLDLR Double Nickase Plasmid (h) - sc-401310-NIC from Santa Cruz Biotechnology
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VLDLR Double Nickase Plasmid (h2) - sc-401310-NIC-2 from Santa Cruz Biotechnology
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VLDLR CRISPR Activation Plasmid (h) - sc-401310-ACT from Santa Cruz Biotechnology
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VLDLR CRISPR Activation Plasmid (h2) - sc-401310-ACT-2 from Santa Cruz Biotechnology
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VLDLR Lentiviral Activation Particles (h) - sc-401310-LAC from Santa Cruz Biotechnology
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VLDLR Lentiviral Activation Particles (h2) - sc-401310-LAC-2 from Santa Cruz Biotechnology
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VLDLR siRNA (h) - sc-36822 from Santa Cruz Biotechnology
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VLDLR shRNA Plasmid (h) - sc-36822-SH from Santa Cruz Biotechnology
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VLDLR shRNA (h) Lentiviral Particles - sc-36822-V from Santa Cruz Biotechnology
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VLDL R RNAi - H00007436-R01 from Novus Biologicals
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VLDL R RNAi - H00007436-R02 from Novus Biologicals
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MISSION® esiRNA - EHU091521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22691 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05047 from Sigma-Aldrich
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VLDLR siRNA (Human) - CRH5089 from Cohesion Biosciences
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VLDLR - MBS8240175 from MyBioSource
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shRNA set against Human Vldlr (NM_003383.3) - SHH442848 from Creative biogene
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shRNA set against Human VLDLR(NM_001018056.1) - SHL126324 from Creative biogene
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shRNA set against Human VLDLR(NM_003383.3) - SHL126378 from Creative biogene
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Human VLDLR siRNA - orb265591 from Biorbyt
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VLDLR shRNA Plasmid (Human) - CHH5089 from Cohesion Biosciences
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VLDLR miRNA 3'UTR clone - MiUTR1H-11125 from Creative biogene
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