Gene Symbol | GSTA3 |
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Entrez Gene | 2940 |
Alt Symbol | GSTA3-3, GTA3 |
Species | Human |
Gene Type | protein-coding |
Description | glutathione S-transferase alpha 3 |
Other Description | GST class-alpha member 3|S-(hydroxyalkyl)glutathione lyase A3|glutathione S-alkyltransferase A3|glutathione S-aralkyltransferase A3|glutathione S-aryltransferase A3|glutathione S-transferase A3|glutathione S-transferase A3-3 |
Swissprots | Q9H415 Q16772 Q068V6 Q8WWA8 O43468 |
Accessions | AAA74634 ABI75350 EAX04390 EAX04391 Q16772 AA846513 AF020919 AAD04712 AF508266 AAM33360 AI199811 BC020619 AAH20619 BG573805 DQ891389 ABM82315 DQ894564 ABM85490 DT932587 XM_006715072 XP_006715135 XM_011514533 XP_011512835 XR_926166 XR_926167 NM_000847 NP_000838 |
Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)- pregnene-3,20-dione, precursors to testosterone and progesterone, respectively. {ECO:0000269|PubMed:15595823, ECO:0000269|PubMed:20083122}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450 |
GSTA3 CRISPR/Cas9 KO Plasmid (h) - sc-410805 from Santa Cruz Biotechnology
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GSTA3 HDR Plasmid (h) - sc-410805-HDR from Santa Cruz Biotechnology
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GSTA3 Double Nickase Plasmid (h) - sc-410805-NIC from Santa Cruz Biotechnology
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GSTA3 Double Nickase Plasmid (h2) - sc-410805-NIC-2 from Santa Cruz Biotechnology
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GSTA3 CRISPR Activation Plasmid (h) - sc-410805-ACT from Santa Cruz Biotechnology
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GSTA3 CRISPR Activation Plasmid (h2) - sc-410805-ACT-2 from Santa Cruz Biotechnology
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GSTA3 Lentiviral Activation Particles (h) - sc-410805-LAC from Santa Cruz Biotechnology
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GSTA3 Lentiviral Activation Particles (h2) - sc-410805-LAC-2 from Santa Cruz Biotechnology
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GSTA3 siRNA (h) - sc-105423 from Santa Cruz Biotechnology
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GSTA3 shRNA Plasmid (h) - sc-105423-SH from Santa Cruz Biotechnology
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GSTA3 shRNA (h) Lentiviral Particles - sc-105423-V from Santa Cruz Biotechnology
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GSTA3 RNAi - H00002940-R01 from Novus Biologicals
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MISSION® esiRNA - EHU127031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9732 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9732 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00625 from Sigma-Aldrich
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GSTA3 siRNA (Human) - CRH1988 from Cohesion Biosciences
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GSTA3 - MBS8207647 from MyBioSource
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shRNA set against Human GSTA3 (NM_000847.4) - SHH308562 from Creative biogene
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Human GSTA3 siRNA - orb262490 from Biorbyt
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GSTA3 shRNA Plasmid (Human) - CHH1988 from Cohesion Biosciences
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GSTA3 miRNA 3'UTR clone - MiUTR3H-07678 from Creative biogene
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