Gene Symbol | DERA |
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Entrez Gene | 51071 |
Alt Symbol | CGI-26, DEOC |
Species | Human |
Gene Type | protein-coding |
Description | deoxyribose-phosphate aldolase (putative) |
Other Description | 2-deoxy-D-ribose 5-phosphate aldolase|2-deoxyribose-5-phosphate aldolase homolog|deoxyriboaldolase|deoxyribose-phosphate aldolase|phosphodeoxyriboaldolase|putative deoxyribose-phosphate aldolase |
Swissprots | Q9Y315 Q6PHW2 Q53HN9 |
Accessions | EAW96357 EAW96358 EAW96359 Q9Y315 AF132960 AAD27735 AK024614 AK222541 BAD96261 AK296697 BAG59291 AK309182 BC041328 BC056234 AAH56234 BC152913 AAI52914 BU928832 CB851336 NM_001300779 NP_001287708 NM_015954 NP_057038 |
Function | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation. {ECO:0000269|PubMed:25229427}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:25229427}. Cytoplasmic granule {ECO:0000269|PubMed:25229427}. Nucleus {ECO:0000269|PubMed:25229427}. Note=Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation. {ECO:0000269|PubMed:25229427}. |
Tissue Specificity | Mainly expressed in liver, lung and colon. {ECO:0000269|PubMed:25229427}. |
Top Pathways | Pentose phosphate pathway |
Human DERA full length protein - ab113155 from Abcam
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DERA Antibody Blocking Peptide - LS-E23151 from LifeSpan Bioscience
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DERA Antibody Blocking Peptide - LS-E9764 from LifeSpan Bioscience
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DERA Protein - NBP2-22649 from Novus Biologicals
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Recombinant Human DERA Protein - NBP1-78809 from Novus Biologicals
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DERA Recombinant Protein - P3947 from Novus Biologicals
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DERA-Antibody-N-term-Blocking-Peptide - BP8764a from Abgent, a WuXi AppTec company
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Human DERA protein - orb168225 from Biorbyt
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E. coli DERA (1-259 a.a.) protein - orb168223 from Biorbyt
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Human PYCR2 protein - orb168224 from Biorbyt
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DERA protein (His tag) - 80R-1954 from Fitzgerald
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DERA (1-318, His-tag) - AR39138PU-L from Acris Antibodies
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DERA (1-318, His-tag) - AR39138PU-N from Acris Antibodies
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DERA - P3947 from Acris Antibodies
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Recombinant Deoxyribose-Phosphate Aldolase E.Coli - 228-12270-1 from RayBiotech
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Recombinant Deoxyribose-Phosphate Aldolase E.Coli - 228-12270-2 from RayBiotech
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Recombinant Deoxyribose-Phosphate Aldolase E.Coli - 228-12270-3 from RayBiotech
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Deoxyribose-Phosphate Aldolase E.Coli Recombinant - 228-12278-1 from RayBiotech
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Deoxyribose-Phosphate Aldolase, Human Recombinant - 228-12321-1 from RayBiotech
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Recombinant Deoxyribose-Phosphate Aldolase Human - 228-12321-2 from RayBiotech
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Recombinant Deoxyribose-Phosphate Aldolase Human - 228-12321-3 from RayBiotech
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DERA, 1-318aa, Human, His tag, E.coli - 01-P1196 from ARP American Research Products
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DERA E.coli (1-259 a.a.) - ENPS-134 from NeoScientific
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DERA Human - ENPS-177 from NeoScientific
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Recombinant E. Coli DERA Enzyme - BP002486-ENZ-118 from Syd Labs
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