| Gene Symbol | MAPK8IP3 |
|---|---|
| Entrez Gene | 23162 |
| Alt Symbol | JIP-3, JIP3, JSAP1, SYD2, syd |
| Species | Human |
| Gene Type | protein-coding |
| Description | mitogen-activated protein kinase 8 interacting protein 3 |
| Other Description | C-Jun-amino-terminal kinase-interacting protein 3|C-jun-amino-terminal kinase interacting protein 3|JNK MAP kinase scaffold protein 3|JNK-interacting protein 3|JNK/SAPK-associated protein-1|JNK/stress-activated protein kinase-associated protein 1|homolog of Drosophila Sunday driver 2|mitogen-activated protein kinase 8-interacting protein 3 |
| Swissprots | Q9H7P1 Q9NUG0 Q9UPT6 A2A2B3 A7E2B3 Q9H4I4 Q96RY4 |
| Accessions | AAK61290 CAB72318 EAW85630 EAW85631 EAW85632 EAW85633 Q9UPT6 AB028989 BAA83018 AB621811 BAK64147 AI291346 AK024437 BAB15727 BC087861 BC137123 AAI37124 BC137124 AAI37125 BC144486 AAI44487 BC150266 AAI50267 BM791368 BQ083050 BQ231003 BQ961808 BY795428 CA776361 CD557812 CN361410 CN405914 CN405915 CR749696 CAH18476 XM_005255187 XP_005255244 XM_005255190 XP_005255247 XM_006720869 XP_006720932 XM_011522429 XP_011520731 XM_011522430 XP_011520732 XM_011522431 XP_011520733 XM_011522432 XP_011520734 XM_011522433 XP_011520735 NM_001040439 NP_001035529 NM_015133 NP_055948 |
| Function | The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. |
| Top Pathways | MAPK signaling pathway |
JIP-3 siRNA (h) - sc-37123 from Santa Cruz Biotechnology
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JIP-3 shRNA Plasmid (h) - sc-37123-SH from Santa Cruz Biotechnology
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JIP-3 shRNA (h) Lentiviral Particles - sc-37123-V from Santa Cruz Biotechnology
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JIP-3 CRISPR/Cas9 KO Plasmid (h) - sc-401970 from Santa Cruz Biotechnology
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JIP-3 HDR Plasmid (h) - sc-401970-HDR from Santa Cruz Biotechnology
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JIP-3 Double Nickase Plasmid (h) - sc-401970-NIC from Santa Cruz Biotechnology
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JIP-3 Double Nickase Plasmid (h2) - sc-401970-NIC-2 from Santa Cruz Biotechnology
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JIP-3 CRISPR Activation Plasmid (h) - sc-401970-ACT from Santa Cruz Biotechnology
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JIP-3 CRISPR Activation Plasmid (h2) - sc-401970-ACT-2 from Santa Cruz Biotechnology
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JIP-3 Lentiviral Activation Particles (h) - sc-401970-LAC from Santa Cruz Biotechnology
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JIP-3 Lentiviral Activation Particles (h2) - sc-401970-LAC-2 from Santa Cruz Biotechnology
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JIP-3 siRNA (h2) - sc-43368 from Santa Cruz Biotechnology
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JIP-3 shRNA Plasmid (h2) - sc-43368-SH from Santa Cruz Biotechnology
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JIP-3 shRNA (h2) Lentiviral Particles - sc-43368-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU090031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13018 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13018 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09459 from Sigma-Aldrich
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MAPK8IP3 siRNA (Human) - CRH8045 from Cohesion Biosciences
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shRNA set against Human Mapk8ip3 (NM_015133.3) - SHH338111 from Creative biogene
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shRNA set against Human MAPK8IP3(NM_001040439.1) - SHH176159 from Creative biogene
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Human MAPK8IP3 siRNA - orb268547 from Biorbyt
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MAPK8IP3 shRNA Plasmid (Human) - CHH8045 from Cohesion Biosciences
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MAPK8IP3 miRNA 3'UTR clone - MiUTR1H-06092 from Creative biogene
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MAPK8IP3 miRNA 3'UTR clone - MiUTR1H-06093 from Creative biogene
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