Gene Symbol | SULT1B1 |
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Entrez Gene | 27284 |
Alt Symbol | ST1B1, ST1B2, SULT1B2 |
Species | Human |
Gene Type | protein-coding |
Description | sulfotransferase family, cytosolic, 1B, member 1 |
Other Description | sulfotransferase 1B1|sulfotransferase 1B2|sulfotransferase family cytosolic 1B member 1|thyroid hormone sulfotransferase |
Swissprots | Q9UK34 Q96FI1 O43704 O15497 |
Accessions | AAF05917 EAX05595 O43704 BC010895 AAH10895 BG461453 D89479 BAA24547 U95726 AAB65154 XM_005265676 XP_005265733 XM_005265677 XP_005265734 XM_005265678 XP_005265735 XM_011531873 XP_011530175 NM_014465 NP_055280 |
Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine. {ECO:0000269|PubMed:9443824, ECO:0000269|PubMed:9463486}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Highly expressed in the liver, peripheral blood leukocytes, colon (mucosal lining), small intestine (jejunum) and spleen. A lesser expression was observed in the lung, placenta and thymus. {ECO:0000269|PubMed:9463486}. |
Human SULT1B1 full length protein - ab126691 from Abcam
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Human SULT1B1 full length protein - ab172823 from Abcam
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SULT1B1 Antibody Blocking Peptide - LS-E4346 from LifeSpan Bioscience
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SULT1B1 Antibody Blocking Peptide - LS-E17628 from LifeSpan Bioscience
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SULT1B1 Antibody Blocking Peptide - LS-E17629 from LifeSpan Bioscience
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Cytosolic Sulfotransferase 1B1/SULT1B1 Recombinant Protein - H00027284-P01 from Novus Biologicals
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Cytosolic Sulfotransferase 1B1/SULT1B1 Partial Recombinant Protein - H00027284-Q01 from Novus Biologicals
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Recombinant Human Cytosolic Sulfotransferase 1B1/SULT1B1 Protein - NBP1-98990 from Novus Biologicals
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SULT1B1-Antibody-C-term-Blocking-Peptide - BP16645b from Abgent, a WuXi AppTec company
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Recombinant Human SULT1B1, CF - 5959-ST-020 from R&D Systems
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Human Cytosolic Sulfotransferase 1B1 protein - orb163516 from Biorbyt
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Human SULT1B1 protein - orb169375 from Biorbyt
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Human SULT1B1 His tag protein - orb83864 from Biorbyt
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SULT1B1 Blocking Peptide - 33R-6218 from Fitzgerald
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SULT1B1 Blocking Peptide - 33R-4623 from Fitzgerald
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SULT1B1 protein (His tag) - 80R-2277 from Fitzgerald
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SULT1B1 (1-296, His-tag) - AR50361PU-N from Acris Antibodies
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SULT1B1 (1-296, His-tag) - AR50361PU-S from Acris Antibodies
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SULT1B1 - H00027284-P01-02 from Acris Antibodies
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SULT1B1 - H00027284-Q01-10 from Acris Antibodies
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SULT1B1 - H00027284-Q01-25 from Acris Antibodies
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SULT1B1, 1-296aa, Human, His tag, E.coli - 01-P1537 from ARP American Research Products
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SULT1B1, Human, Recombinant - 19-CF90 from ARP American Research Products
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SULT1B1 fusion protein - Ag9009 from Proteintech Group
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SULT1B1 fusion protein - Ag8993 from Proteintech Group
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