Gene Symbol | HK2 |
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Entrez Gene | 3099 |
Alt Symbol | HKII, HXK2 |
Species | Human |
Gene Type | protein-coding |
Description | hexokinase 2 |
Other Description | HK II|hexokinase type II|hexokinase-2|hexokinase-2, muscle|muscle form hexokinase |
Swissprots | P52789 Q9UN82 Q8WU87 D6W5J2 |
Accessions | AAT38114 AAX93084 AAY24209 ABI49509 BAA04999 CAA86476 CAA86482 CBF63160 CBU88036 EAW99601 EAW99602 EAW99603 P52789 AF086198 AF148513 AAD30174 AI085541 AI278414 AK290357 BAF83046 AW134604 BC021116 AAH21116 BC064369 AAH64369 BM706373 BM912287 CB160837 CR749202 CAH18060 DQ895770 ABM86696 EU176361 ABW03812 XM_005264280 XP_005264337 XM_011532807 XP_011531109 NM_000189 NP_000180 |
Subcellular Location | Mitochondrion outer membrane {ECO:0000250}. Note=Its hydrophobic N-terminal sequence may be involved in membrane binding. {ECO:0000250}. |
Tissue Specificity | Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. |
Top Pathways | Glycolysis / Gluconeogenesis, Central carbon metabolism in cancer, Carbohydrate digestion and absorption, Type II diabetes mellitus, Insulin signaling pathway |
SignalSilence ® Hexokinase II siRNA I - 14178 from Cell Signaling Technology
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HXK II CRISPR/Cas9 KO Plasmid (h) - sc-400611 from Santa Cruz Biotechnology
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HXK II HDR Plasmid (h) - sc-400611-HDR from Santa Cruz Biotechnology
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HXK II Double Nickase Plasmid (h) - sc-400611-NIC from Santa Cruz Biotechnology
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HXK II Double Nickase Plasmid (h2) - sc-400611-NIC-2 from Santa Cruz Biotechnology
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HXK II CRISPR Activation Plasmid (h) - sc-400611-ACT from Santa Cruz Biotechnology
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HXK II CRISPR Activation Plasmid (h2) - sc-400611-ACT-2 from Santa Cruz Biotechnology
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HXK II Lentiviral Activation Particles (h) - sc-400611-LAC from Santa Cruz Biotechnology
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HXK II Lentiviral Activation Particles (h2) - sc-400611-LAC-2 from Santa Cruz Biotechnology
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HXK II siRNA (h) - sc-35621 from Santa Cruz Biotechnology
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HXK II shRNA Plasmid (h) - sc-35621-SH from Santa Cruz Biotechnology
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HXK II shRNA (h) Lentiviral Particles - sc-35621-V from Santa Cruz Biotechnology
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MISSION® siRNA - SIHK0914 from Sigma-Aldrich
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MISSION® siRNA - SIHK0916 from Sigma-Aldrich
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MISSION® siRNA - SIHK0915 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1644 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1644 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11525 from Sigma-Aldrich
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HK2 siRNA (Human) - CRH2112 from Cohesion Biosciences
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HK2 - MBS8208411 from MyBioSource
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HXK II CRISPR/Cas9 KO Plasmid (h2) - sc-400611-KO-2 from Santa Cruz Biotechnology
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HXK II HDR Plasmid (h2) - sc-400611-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human Hk2 (NM_000189.4) - SHH313089 from Creative biogene
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shRNA set against Human HK2(NM_000189.4) - SHH124239 from Creative biogene
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Human HK2 siRNA - orb262614 from Biorbyt
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