IRGM

Gene Symbol IRGM
Entrez Gene 345611
Alt Symbol IFI1, IRGM1, LRG-47, LRG47
Species Human
Gene Type protein-coding
Description immunity-related GTPase family, M
Other Description LPS-stimulated RAW 264.7 macrophage protein 47 homolog|LRG-47-like protein|immunity-related GTPase family M protein|immunity-related GTPase family, M1|interferon-inducible protein 1
Swissprots B3VEX0 A1A4Y4
Accessions A1A4Y4 ACO88909 BAJ13476 BAJ13477 BC038539 BC128167 AAI28168 BC128168 AAI28169 EU742619 ACF21844 XM_011537641 XP_011535943 XR_944324 NM_001145805 NP_001139277
Function Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity). {ECO:0000250}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}. Cell membrane {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000250}. Cell projection, phagocytic cup {ECO:0000250}. Note=Behaves like an integral membrane protein. Recruited to the plasma membrane around forming phagocytic cups, it remains associated with maturing autophagosomes. Preferentially associated with cis- and medial-Golgi. {ECO:0000250}.
Tissue Specificity Widely expressed (at protein level). Expressed in several tissues including colon, small bowel and peripheral blood leukocytes. {ECO:0000269|PubMed:16888103, ECO:0000269|PubMed:17554261}.
Top Pathways Toxoplasmosis

immunity-related GTPase family, M, ELISA Kit - MBS9320915 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/ml.
Range 3.12 ng/ml - 100 ng/ml.

Human IRGM ELISA Kit - E086925 from Biobool

Category ELISA Kit

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9367093 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9348831 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9344751 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
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Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9362125 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9359903 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9358556 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9349051 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9367961 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9377588 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9369231 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9347211 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9366350 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Immunity-Related GTPase Family M Protein (IRGM), ELISA Kit - MBS9362266 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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