Gene Symbol | HIST1H1E |
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Entrez Gene | 3008 |
Alt Symbol | H1.4, H1E, H1F4, H1s-4, dJ221C16.5 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H1e |
Other Description | H1 histone family, member 4|histone 1, H1e|histone H1.4|histone H1b|histone H1s-4 |
Swissprots | Q4VB25 P10412 |
Accessions | AAA63187 AAN06702 EAW55534 P10412 AK313681 BAG36431 BC055095 BC096168 AAH96168 BC096169 AAH96169 BC096170 AAH96170 BC099632 AAH99632 EF065554 ABN72276 EF065555 ABN72277 NM_005321 NP_005312 |
Function | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Chromosome. Note=Mainly localizes in heterochromatin. Dysplays a punctuate staining pattern in the nucleus. |
Histone cluster 1 H1E CRISPR/Cas9 KO Plasmid (h) - sc-402775 from Santa Cruz Biotechnology
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Histone cluster 1 H1E HDR Plasmid (h) - sc-402775-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H1E Double Nickase Plasmid (h) - sc-402775-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H1E Double Nickase Plasmid (h2) - sc-402775-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1E CRISPR Activation Plasmid (h) - sc-402775-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H1E CRISPR Activation Plasmid (h2) - sc-402775-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1E Lentiviral Activation Particles (h) - sc-402775-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H1E Lentiviral Activation Particles (h2) - sc-402775-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H1E siRNA (h) - sc-37974 from Santa Cruz Biotechnology
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Histone cluster 1 H1E shRNA Plasmid (h) - sc-37974-SH from Santa Cruz Biotechnology
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Histone cluster 1 H1E shRNA (h) Lentiviral Particles - sc-37974-V from Santa Cruz Biotechnology
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Histone H1.4 RNAi - H00003008-R01 from Novus Biologicals
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MISSION® esiRNA - EHU038891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10054 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10054 from Sigma-Aldrich
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HIST1H1E siRNA (Human) - CRH2043 from Cohesion Biosciences
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HIST1H1E - MBS8227928 from MyBioSource
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shRNA set against Human HIST1H1E (NM_005321.2) - SHH312401 from Creative biogene
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Human HIST1H1E siRNA - orb262545 from Biorbyt
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HIST1H1E shRNA Plasmid (Human) - CHH2043 from Cohesion Biosciences
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HIST1H1E miRNA 3'UTR clone - MiUTR1H-04517 from Creative biogene
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