ACTL6B

Gene Symbol ACTL6B
Entrez Gene 51412
Alt Symbol ACTL6, BAF53B
Species Human
Gene Type protein-coding
Description actin-like 6B
Other Description 53 kDa BRG1-associated factor B|BRG1-associated factor 53B|actin-like 6|actin-like protein 6B|actin-related protein Baf53b|arpNalpha|hArpN alpha
Swissprots O75421 O94805 A4D2D0
Accessions AAP21874 EAL23823 EAW76502 EAW76503 EAW76504 EAW76505 O94805 AB015906 BAA74576 AF041475 AAD54678 AK314940 BAG37446 BC008582 BC020944 AAH20944 BM696009 HQ447891 ADQ32375 XR_927476 NM_016188 NP_057272
Function Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multi
Subcellular Location Nucleus.

BAF53B CRISPR/Cas9 KO Plasmid (h) - sc-409940 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAF53B HDR Plasmid (h) - sc-409940-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAF53B Double Nickase Plasmid (h) - sc-409940-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAF53B Double Nickase Plasmid (h2) - sc-409940-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAF53B CRISPR Activation Plasmid (h) - sc-409940-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAF53B CRISPR Activation Plasmid (h2) - sc-409940-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAF53B Lentiviral Activation Particles (h) - sc-409940-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAF53B Lentiviral Activation Particles (h2) - sc-409940-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAF53B siRNA (h) - sc-105113 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAF53B shRNA Plasmid (h) - sc-105113-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAF53B shRNA (h) Lentiviral Particles - sc-105113-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU139251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2774 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2774 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ACTL6B siRNA (Human) - CRH9752 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACTL6B - MBS8231460 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ACTL6B (NM_016188.4) - SHH230974 from Creative biogene

Category siRNA
Species Reactivities Human

Human ACTL6B siRNA - orb270254 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ACTL6B shRNA Plasmid (Human) - CHH9752 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ACTL6B miRNA 3'UTR clone - MiUTR3H-12452 from Creative biogene

Species Reactivities Human
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