Gene Symbol |
HSP31
|
Entrez Gene |
852146
|
Alt Symbol |
-
|
Species |
Yeast
|
Gene Type |
protein-coding
|
Description |
Hsp31p
|
Other Description |
-
|
Swissprots |
Q04432 E9P8V9 D6VTF4
|
Accessions |
DAA12364 Q04432 NM_001180841 NP_010822
|
Function |
Catalyzes the conversion of methylglyoxal (MG) to D- lactate in a single glutathione (GSH)-independent step. May play a role in detoxifying endogenously produced glyoxals (PubMed:24302734). Involved in protection against reactive oxygen species (ROS) (PubMed:17395014). Important for viability in stationary phase. May negatively regulate TORC1 in response to nutrient limitation (PubMed:24706893). {ECO:0000269|PubMed:17395014, ECO:0000269|PubMed:24302734, ECO:0000269|PubMed:24706893}.
|
Subcellular Location |
Cytoplasm, P-body {ECO:0000269|PubMed:24706893}. Note=Present in processing bodies (P-bodies) and stress granule (SG) foci upon glucose starvation and heat shock. {ECO:0000269|PubMed:24706893}.
|