SNX33

Gene Symbol SNX33
Entrez Gene 257364
Alt Symbol SH3PX3, SH3PXD3C, SNX30
Species Human
Gene Type protein-coding
Description sorting nexin 33
Other Description SH3 and PX domain containing 3|SH3 and PX domain-containing protein 3|sorting nexin-33
Swissprots B1NM17 Q8WV41
Accessions CAL48182 CCQ43875 EAW99243 Q8WV41 AK091291 AK126563 AL833039 CAH56299 BC018775 AAH18775 DQ891695 ABM82621 DQ895211 ABM86137 EF219141 ABN09670 EF653821 ABV26009 EU831407 ACE87094 EU831499 ACE86418 NM_153271 NP_695003
Function Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes. {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:18419754, ECO:0000269|PubMed:19487689, ECO:0000269|PubMed:20964629, ECO:0000269|PubMed:21048941, ECO:0000269|PubMed:22718350}.
Subcellular Location Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic, but a minor proportion is membrane-bound (PubMed:18353773). Not associated with membranes (PubMed:21048941). {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:21048941}.
Tissue Specificity Detected in heart and pancreas. {ECO:0000269|PubMed:18353773}.

SNX33 CRISPR/Cas9 KO Plasmid (h) - sc-408354 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX33 HDR Plasmid (h) - sc-408354-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX33 Double Nickase Plasmid (h) - sc-408354-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX33 Double Nickase Plasmid (h2) - sc-408354-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX33 CRISPR Activation Plasmid (h) - sc-408354-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX33 CRISPR Activation Plasmid (h2) - sc-408354-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX33 Lentiviral Activation Particles (h) - sc-408354-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX33 Lentiviral Activation Particles (h2) - sc-408354-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SNX33 siRNA (h) - sc-89967 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNX33 shRNA Plasmid (h) - sc-89967-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNX33 shRNA (h) Lentiviral Particles - sc-89967-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU061251 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20310 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20310 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12636 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12636

SNX33 siRNA (Human) - CRJ6791 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNX33 RNAi - H00257364-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
RNAi sequence position: SNX33 RNAi [h00257364-R01] - Position of the Chimera RNAi.

SNX33 - MBS8211833 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SNX33 (NM_153271.1) - SHH414820 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SH3PX3(NM_153271.1) - SHR223320 from Creative biogene

Category siRNA
Species Reactivities Human

Human SNX33 siRNA - orb277292 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SNX33 shRNA Plasmid (Human) - CHJ6791 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SNX33 miRNA 3'UTR clone - MiUTR1H-09366 from Creative biogene

Species Reactivities Human
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