Gene Symbol | CFP |
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Entrez Gene | 5199 |
Alt Symbol | BFD, PFC, PFD, PROPERDIN |
Species | Human |
Gene Type | protein-coding |
Description | complement factor properdin |
Other Description | complement factor P|properdin|properdin P factor, complement |
Swissprots | O15134 P27918 O15136 O75826 O15135 |
Accessions | AAB62886 AAB63279 AAB63280 AAC51626 AAP43692 CAA50220 CCO13706 EAW59317 EAW59318 EAW59319 EAW59320 P27918 AK122955 BAG53818 AK310695 BC015756 AAH15756 DB146591 DQ893460 ABM84386 DQ896310 ABM87309 M83652 AAA36489 X57748 CAA40914 NM_001145252 NP_001138724 NM_002621 NP_002612 |
Function | A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. {ECO:0000269|PubMed:20382442}. |
Subcellular Location | Secreted. |
Top Pathways | Herpes simplex infection |
Properdin CRISPR/Cas9 KO Plasmid (h) - sc-403967 from Santa Cruz Biotechnology
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Properdin HDR Plasmid (h) - sc-403967-HDR from Santa Cruz Biotechnology
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Properdin Double Nickase Plasmid (h) - sc-403967-NIC from Santa Cruz Biotechnology
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Properdin Double Nickase Plasmid (h2) - sc-403967-NIC-2 from Santa Cruz Biotechnology
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Properdin CRISPR Activation Plasmid (h) - sc-403967-ACT from Santa Cruz Biotechnology
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Properdin CRISPR Activation Plasmid (h2) - sc-403967-ACT-2 from Santa Cruz Biotechnology
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Properdin Lentiviral Activation Particles (h) - sc-403967-LAC from Santa Cruz Biotechnology
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Properdin Lentiviral Activation Particles (h2) - sc-403967-LAC-2 from Santa Cruz Biotechnology
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Properdin siRNA (h) - sc-72082 from Santa Cruz Biotechnology
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Properdin shRNA Plasmid (h) - sc-72082-SH from Santa Cruz Biotechnology
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Properdin shRNA (h) Lentiviral Particles - sc-72082-V from Santa Cruz Biotechnology
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Properdin RNAi - H00005199-R01 from Novus Biologicals
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MISSION® esiRNA - EHU021661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6010 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6010 from Sigma-Aldrich
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CFP siRNA (Human) - CRH3471 from Cohesion Biosciences
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CFP - MBS8201329 from MyBioSource
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shRNA set against Human CFP (NM_002621.2) - SHH262517 from Creative biogene
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CFP shRNA Plasmid (Human) - CHH3471 from Cohesion Biosciences
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CFP miRNA 3'UTR clone - MiUTR3H-02727 from Creative biogene
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CFP miRNA 3'UTR clone - MiUTR3H-02728 from Creative biogene
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