Gene Symbol | UNC50 |
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Entrez Gene | 25972 |
Alt Symbol | GMH1, HSD23, UNCL, URP |
Species | Human |
Gene Type | protein-coding |
Description | unc-50 homolog (C. elegans) |
Other Description | PDLs22|geal-6 membrane-associated high-copy suppressor 1|hGMH1|periodontal ligament-specific protein 22|protein GMH1 homolog|protein unc-50 homolog|unc-50 related|uncoordinated-like protein |
Swissprots | Q6X7B9 Q53TD6 D3DVH4 Q53HI1 Q9Y4S6 Q5U5U2 Q53S98 Q9UQF4 |
Accessions | AAX93232 AAY14975 EAX01900 EAX01901 EAX01902 Q53HI1 AF077038 AAD27771 AK222599 BAD96319 AL080115 CAB45714 AY017215 AAK08987 AY251534 AAP20057 BC017019 AAH17019 BC025992 AAH25992 BC039078 AAH39078 BC091481 AAH91481 CR533464 CAG38495 HQ447350 ADQ31836 XM_005263913 XP_005263970 XM_006712403 XP_006712466 XM_006712404 XP_006712467 XM_011510930 XP_011509232 NM_014044 NP_054763 |
Function | May be involved in cell surface expression of neuronal nicotinic receptors. Binds RNA (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus inner membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000269|PubMed:12808035}; Multi-pass membrane protein {ECO:0000269|PubMed:12808035}. |
Tissue Specificity | Present in periodontal ligament fibroblasts (at protein level). {ECO:0000269|PubMed:17004066}. |
UNCL CRISPR/Cas9 KO Plasmid (h) - sc-410497 from Santa Cruz Biotechnology
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UNCL HDR Plasmid (h) - sc-410497-HDR from Santa Cruz Biotechnology
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UNCL Double Nickase Plasmid (h) - sc-410497-NIC from Santa Cruz Biotechnology
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UNCL Double Nickase Plasmid (h2) - sc-410497-NIC-2 from Santa Cruz Biotechnology
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UNCL CRISPR Activation Plasmid (h) - sc-410497-ACT from Santa Cruz Biotechnology
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UNCL CRISPR Activation Plasmid (h2) - sc-410497-ACT-2 from Santa Cruz Biotechnology
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UNCL Lentiviral Activation Particles (h) - sc-410497-LAC from Santa Cruz Biotechnology
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UNCL Lentiviral Activation Particles (h2) - sc-410497-LAC-2 from Santa Cruz Biotechnology
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UNCL siRNA (h) - sc-94346 from Santa Cruz Biotechnology
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UNCL shRNA Plasmid (h) - sc-94346-SH from Santa Cruz Biotechnology
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UNCL shRNA (h) Lentiviral Particles - sc-94346-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22499 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22499 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00960 from Sigma-Aldrich
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UNC50 siRNA (Human) - CRH8623 from Cohesion Biosciences
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UNC50 - MBS8218691 from MyBioSource
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shRNA set against Human UNC50 (NM_014044.5) - SHH440548 from Creative biogene
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shRNA set against Human UNC50(NM_014044.5) - SHL114704 from Creative biogene
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Human UNC50 siRNA - orb269125 from Biorbyt
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UNC50 shRNA Plasmid (Human) - CHH8623 from Cohesion Biosciences
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UNC50 miRNA 3'UTR clone - MiUTR1H-11015 from Creative biogene
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