PNP

Gene Symbol PNP
Entrez Gene 4860
Alt Symbol NP, PRO1837, PUNP
Species Human
Gene Type protein-coding
Description purine nucleoside phosphorylase
Other Description HEL-S-156an|epididymis secretory sperm binding protein Li 156an|inosine phosphorylase|inosine-guanosine phosphorylase|purine-nucleoside:orthophosphate ribosyltransferase
Swissprots Q15160 B2R8S5 P00491 D3DS00 Q5PZ03
Accessions AAA36460 AAV68044 EAW66458 EAW66459 P00491 AK098544 BAC05327 AK126154 AK307340 AK307364 AK313490 BAG36272 BC104206 AAI04207 BC104207 AAI04208 BC106074 AAI06075 BM193354 BU622706 CR407607 CAG28535 EU794649 ACJ13703 X00737 CAA25320 NM_000270 NP_000261
Function The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. {ECO:0000269|PubMed:2104852}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:22509282}.
Tissue Specificity Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. {ECO:0000269|PubMed:22509282}.
Top Pathways Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism

NP-Over-expression-Lysate - LY10284a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag NP (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NP gene (Lane 2, Cat. #LY10284a).

PNP 293 Cell Lysate - 410285 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Purine Nucleoside Phosphorylase/PNP Overexpression Lysate (Native) - NBL1-13737 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Nucleoside phosphorylase Overexpression Lysate (Adult Normal) [NBL1-13737] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Nucleoside phosphorylase.

PNP (h): 293T Lysate - sc-111683 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

PNP Over-expression Lysate Product - GWB-4538EC from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

MERS-CoV (NCoV / Novel coronavirus) Nucleoprotein / NP Insect Cell Lysate (WB positive control) - 40068-V08BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species MERS-CoV

Influenza A H1N1 (A/California/07/2009) Nucleoprotein / NP Insect Cell Lysate (WB positive control) - 40205-V08BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species H1N1

Human SARS Coronavirus Nucleoprotein / NP Insect Cell Lysate (WB positive control) - 40143-V08BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species SARS

Influenza A H2N2 Nucleoprotein / NP Insect Cell Lysate (WB positive control) - 40033-V08BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species H2N2

Influenza A H1N1 Nucleoprotein / NP Insect Cell Lysate (WB positive control) - 11675-V08BL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species H1N1

Panoply™ Human PNP Knockdown Stable Cell Line - CSC-DC012035 from Creative biogene

Category Cell Line
Species Human

PNP KO Cell Lysate-HEK293T - CLKO-0796 from Creative biogene

Category Cell Lysate
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