Gene Symbol | MGAM |
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Entrez Gene | 8972 |
Alt Symbol | MG, MGA |
Species | Human |
Gene Type | protein-coding |
Description | maltase-glucoamylase |
Other Description | brush border hydrolase|maltase-glucoamylase (alpha-glucosidase)|maltase-glucoamylase, intestinal |
Swissprots | Q86UM5 Q75ME7 O43451 Q0VAX6 |
Accessions | AAL83559 AAL83560 AAP21875 AAS07445 EAW83988 EAW83989 O43451 AF016833 AAC39568 AK127838 BC120872 AAI20873 XM_006716168 XP_006716231 XM_011516670 XP_011514972 XM_011516671 XP_011514973 XM_011516672 XP_011514974 XM_011516673 XP_011514975 XM_011516674 XP_011514976 XR_927545 NM_004668 NP_004659 |
Function | May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing. |
Subcellular Location | Apical cell membrane; Single-pass type II membrane protein. Note=Brush border. |
Tissue Specificity | Expressed in small intestine, granulocyte, and kidney but not in salivary gland or pancreas. |
Top Pathways | Carbohydrate digestion and absorption, Galactose metabolism, Starch and sucrose metabolism |
Maltase-glucoamylase CRISPR/Cas9 KO Plasmid (h) - sc-404265 from Santa Cruz Biotechnology
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Maltase-glucoamylase HDR Plasmid (h) - sc-404265-HDR from Santa Cruz Biotechnology
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Maltase-glucoamylase Double Nickase Plasmid (h) - sc-404265-NIC from Santa Cruz Biotechnology
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Maltase-glucoamylase Double Nickase Plasmid (h2) - sc-404265-NIC-2 from Santa Cruz Biotechnology
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Maltase-glucoamylase CRISPR Activation Plasmid (h) - sc-404265-ACT from Santa Cruz Biotechnology
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Maltase-glucoamylase CRISPR Activation Plasmid (h2) - sc-404265-ACT-2 from Santa Cruz Biotechnology
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Maltase-glucoamylase Lentiviral Activation Particles (h) - sc-404265-LAC from Santa Cruz Biotechnology
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Maltase-glucoamylase Lentiviral Activation Particles (h2) - sc-404265-LAC-2 from Santa Cruz Biotechnology
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Maltase-glucoamylase siRNA (h) - sc-75740 from Santa Cruz Biotechnology
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Maltase-glucoamylase shRNA Plasmid (h) - sc-75740-SH from Santa Cruz Biotechnology
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Maltase-glucoamylase shRNA (h) Lentiviral Particles - sc-75740-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU051581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13271 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06969 from Sigma-Aldrich
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MGAM siRNA (Human) - CRH5922 from Cohesion Biosciences
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shRNA set against Human MGAM (NM_004668.2) - SHH341327 from Creative biogene
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MGAM shRNA Plasmid (Human) - CHH5922 from Cohesion Biosciences
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MGAM miRNA 3'UTR clone - MiUTR3H-01377 from Creative biogene
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