| Gene Symbol | Adgre5 |
|---|---|
| Entrez Gene | 26364 |
| Alt Symbol | AA409984, Cd97, TM7LN1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | adhesion G protein-coupled receptor E5 |
| Other Description | CD97 antigen|EGF-TM7 receptor |
| Swissprots | Q9CVI5 Q9Z0M6 Q9JLQ8 Q923A1 |
| Accessions | EDL10917 EDL10918 Q9Z0M6 AF146344 AAF67800 AK004577 BAB23386 AK008101 BAB25461 AK181003 AK216710 AK218664 BB872151 BC006676 AAH06676 CA319344 CD553351 CT010326 CAJ18534 Y18365 CAB38246 XM_006531033 XP_006531096 XM_006531035 XP_006531098 NM_001163029 NP_001156501 NM_001163030 NP_001156502 NM_001163031 NP_001156503 NM_011925 NP_036055 |
| Function | Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. {ECO:0000269|PubMed:14707087}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:10540231}; Multi-pass membrane protein {ECO:0000269|PubMed:10540231}. |
| Tissue Specificity | Although predominantly expressed by cells of the immune system is expressed ubiquitously, with particularly high levels of expression in the lung and the thymus gland. In the spleen, expression is detected on most myeloid cells and variable portions of T-cells, B-cells and NK cells. In the bone marrow, expressed in nearly all myeloid cells, whereas little if any expression is found on erythroid cells. |