Gene Symbol | CNP |
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Entrez Gene | 1267 |
Alt Symbol | CNP1 |
Species | Human |
Gene Type | protein-coding |
Description | 2',3'-cyclic nucleotide 3' phosphodiesterase |
Other Description | 2', 3' cyclic nucleotide 3' phosphohydrolase|2',3'-cyclic-nucleotide 3'-phosphodiesterase|CNPase |
Swissprots | P09543 |
Accessions | AAB23928 AAB24298 BAA02435 BAA39694 EAW60785 EAW60786 EAW60787 P09543 AK026876 AK097833 AK098048 AK098384 AK124861 AK294179 BAG57497 AK295351 BAG58318 AK308696 BC001362 AAH01362 BC006392 AAH06392 BC011046 AAH11046 BC028040 AAH28040 BC045561 CB988051 D28445 BAA05811 DQ892575 ABM83501 DQ895791 ABM86717 M19650 AAA35704 XM_006721701 XP_006721764 XM_011524340 XP_011522642 NM_033133 NP_149124 |
Function | May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. {ECO:0000250}. |
Subcellular Location | Membrane; Lipid-anchor. Melanosome. Note=Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
CNPase CRISPR/Cas9 KO Plasmid (h) - sc-402463 from Santa Cruz Biotechnology
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CNPase HDR Plasmid (h) - sc-402463-HDR from Santa Cruz Biotechnology
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CNPase Double Nickase Plasmid (h) - sc-402463-NIC from Santa Cruz Biotechnology
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CNPase Double Nickase Plasmid (h2) - sc-402463-NIC-2 from Santa Cruz Biotechnology
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CNPase CRISPR Activation Plasmid (h) - sc-402463-ACT from Santa Cruz Biotechnology
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CNPase CRISPR Activation Plasmid (h2) - sc-402463-ACT-2 from Santa Cruz Biotechnology
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CNPase Lentiviral Activation Particles (h) - sc-402463-LAC from Santa Cruz Biotechnology
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CNPase Lentiviral Activation Particles (h2) - sc-402463-LAC-2 from Santa Cruz Biotechnology
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CNPase siRNA (h) - sc-44377 from Santa Cruz Biotechnology
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CNPase shRNA Plasmid (h) - sc-44377-SH from Santa Cruz Biotechnology
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CNPase shRNA (h) Lentiviral Particles - sc-44377-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU156031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6327 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6327 from Sigma-Aldrich
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CNP siRNA (Human) - CRH0887 from Cohesion Biosciences
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CNP - MBS8206570 from MyBioSource
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CNPase CRISPR/Cas9 KO Plasmid (h2) - sc-402463-KO-2 from Santa Cruz Biotechnology
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CNPase HDR Plasmid (h2) - sc-402463-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CNP(NM_033133.4) - SHG187849 from Creative biogene
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Human CNP siRNA - orb261389 from Biorbyt
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CNP shRNA Plasmid (Human) - CHH0887 from Cohesion Biosciences
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CNP miRNA 3'UTR clone - MiUTR1H-02284 from Creative biogene
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