Ch25h

Gene Symbol Ch25h
Entrez Gene 12642
Alt Symbol AI462618, m25OH
Species Mouse
Gene Type protein-coding
Description cholesterol 25-hydroxylase
Other Description cholesterol 25-monooxygenase
Swissprots Q3TUM6 Q8CHQ2 Q9Z0F5
Accessions AAC97480 CAR81283 CBX84761 EDL41749 Q9Z0F5 AF059213 AAC97482 AK140360 BAE24352 AK152770 BAE31482 AK160657 BAE35945 BC039919 AAH39919 NM_009890 NP_034020
Function Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25- hydroxycholesterol by macrophages may play a role in Leydig cell differentiation. {ECO:0000269|PubMed:9852097}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:9852097}; Multi-pass membrane protein {ECO:0000269|PubMed:9852097}.
Tissue Specificity Widely expressed at low level and at higher level in the lung. Weakly expressed in the heart, lung and kidney. {ECO:0000269|PubMed:9852097}.
Top Pathways Primary bile acid biosynthesis

CH25H CRISPR/Cas9 KO Plasmid (m) - sc-419641 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CH25H HDR Plasmid (m) - sc-419641-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CH25H Double Nickase Plasmid (m) - sc-419641-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CH25H Double Nickase Plasmid (m2) - sc-419641-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CH25H CRISPR Activation Plasmid (m) - sc-419641-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CH25H CRISPR Activation Plasmid (m2) - sc-419641-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CH25H Lentiviral Activation Particles (m) - sc-419641-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CH25H Lentiviral Activation Particles (m2) - sc-419641-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

CH25H siRNA (m) - sc-142309 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CH25H shRNA Plasmid (m) - sc-142309-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CH25H shRNA (m) Lentiviral Particles - sc-142309-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN28652 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND28652 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CH25H siRNA (Mouse) - CRM0683 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CH25H - MBS8238215 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse CH25H (NM_009890.1) - SHH262621 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Ch25h(NM_009890.1) - SHG173107 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse CH25H siRNA - orb280159 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CH25H shRNA Plasmid (Mouse) - CHM0683 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

CH25H miRNA 3'UTR clone - MiUTR1M-02980 from Creative biogene

Species Reactivities Mouse
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