| Gene Symbol |
ATP6V1D
|
| Entrez Gene |
100009221
|
| Alt Symbol |
VHA36
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
| Other Description |
V-ATPase 28 kDa accessory protein|V-ATPase subunit D|V-type proton ATPase subunit D|vacuolar proton pump subunit D|vacuolar proton-ATPase subunit D
|
| Swissprots |
O97755
|
| Accessions |
O97755 U45447 AAD10366 NM_001082368 NP_001075837
|
| Function |
Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Localizes to centrosome and the base of the cilium. {ECO:0000250}.
|
| Top Pathways |
Collecting duct acid secretion, Phagosome, Rheumatoid arthritis, Synaptic vesicle cycle, Oxidative phosphorylation
|