Gene Symbol | KRTAP1-3 |
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Entrez Gene | 81850 |
Alt Symbol | KAP1.2, KAP1.3, KAP1.6, KAP1.8A, KAP1.8B, KAP1.9, KRTAP1.3 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 1-3 |
Other Description | keratin associated protein 1.6|keratin-associated protein 1-3|keratin-associated protein 1.8|keratin-associated protein 1.9 |
Swissprots | Q8IUG1 Q9BYS2 Q8IUG0 Q07628 |
Accessions | BAC15620 EAW60698 Q8IUG1 AJ406927 CAC27566 BC069161 AAH69161 BC101150 AAI01151 BC101151 AAI01152 BC101152 AAI01153 BC101153 AAI01154 NM_030966 NP_112228 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone. {ECO:0000269|PubMed:11279113}. |
KRTAP1-3 CRISPR/Cas9 KO Plasmid (h) - sc-413450 from Santa Cruz Biotechnology
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KRTAP1-3 HDR Plasmid (h) - sc-413450-HDR from Santa Cruz Biotechnology
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KRTAP1-3 Double Nickase Plasmid (h) - sc-413450-NIC from Santa Cruz Biotechnology
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KRTAP1-3 Double Nickase Plasmid (h2) - sc-413450-NIC-2 from Santa Cruz Biotechnology
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KRTAP1-3 CRISPR Activation Plasmid (h) - sc-413450-ACT from Santa Cruz Biotechnology
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KRTAP1-3 CRISPR Activation Plasmid (h2) - sc-413450-ACT-2 from Santa Cruz Biotechnology
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KRTAP1-3 Lentiviral Activation Particles (h) - sc-413450-LAC from Santa Cruz Biotechnology
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KRTAP1-3 Lentiviral Activation Particles (h2) - sc-413450-LAC-2 from Santa Cruz Biotechnology
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KRTAP1-3 siRNA (h) - sc-93734 from Santa Cruz Biotechnology
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KRTAP1-3 shRNA Plasmid (h) - sc-93734-SH from Santa Cruz Biotechnology
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KRTAP1-3 shRNA (h) Lentiviral Particles - sc-93734-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11432 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11432 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03579 from Sigma-Aldrich
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KRTAP1-3 siRNA (Human) - CRJ3065 from Cohesion Biosciences
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shRNA set against Human KRTAP1-3(NM_030966.1) - SHH138827 from Creative biogene
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Human KRTAP1-3 siRNA - orb273566 from Biorbyt
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KRTAP1-3 shRNA Plasmid (Human) - CHJ3065 from Cohesion Biosciences
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KRTAP1-3 miRNA 3'UTR clone - MiUTR1H-05491 from Creative biogene
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