TGFA

Gene Symbol TGFA
Entrez Gene 7039
Alt Symbol TFGA
Species Human
Gene Type protein-coding
Description transforming growth factor, alpha
Other Description TGF-alpha|protransforming growth factor alpha
Swissprots A8K286 Q9UKM2 Q15577 Q9UEI3 Q9UKM1 P01135 Q9UKM3 Q53SK7 Q9BS56
Accessions AAA52530 AAA61158 AAA79958 AAD12238 AAD12239 AAF06728 AAF06729 AAF06730 AAF13491 AAP97822 AAY14705 AAY14793 EAW99810 EAW99811 EAW99812 EAW99813 EAW99814 P01135 AF149096 AAF05089 AF149097 AAF05090 AF149098 AAF05091 AK290151 BAF82840 AK309066 AK309220 AK312899 AY548763 AAS83396 BC005308 AAH05308 BI760767 BM453873 BT006833 AAP35479 CD369689 CN274505 DA216480 DA229819 DA373586 DA462271 K03222 AAA61159 M31172 AAA61157 X70340 CAA49806 XM_005264522 XP_005264579 XM_011533076 XP_011531378 NM_001099691 NP_001093161 NM_001308159 NP_001295088 NM_003236 NP_003227 NM_001308158 NP_001295087
Function TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
Subcellular Location Transforming growth factor alpha: Secreted, extracellular space.
Tissue Specificity Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines. {ECO:0000269|PubMed:10523832}.
Top Pathways Non-small cell lung cancer, Renal cell carcinoma, Pancreatic cancer, Glioma, Prostate cancer

Pro-TGF-alpha Antibody - 3715 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from THP-1, Jurkat, and Ramos cells, using Pro-TGF-alpha Antibody.

TGFα (H-50) - sc-9043 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TGFα (H-50): sc-9043. Western blot analysis of human recombinant TGFα fusion protein.

TGFα (V-15) - sc-27155 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TGFα (V-15): sc-27155. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

TGFα (C-18) - sc-1338 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TGFα (C-18): sc-1338. Western blot analysis of human recombinant TGFα.

TGFα (134 A) - sc-36 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
TGFα (134 A): sc-36. Immunofluorescence staining of methanol-fixed A-431 cells showing membrane localization.

TGFα (P/T1) - sc-57447 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-TGF alpha antibody - ab9585 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab9585 at 0.25 µg/ml staining human breast invasive ductal carcinoma tissue by IHC-P.  The antibody was incubated for two hours at room temperature.  An HRP-labeled polymer detection system was used with DAB chromogen. Heat induced antigen retrieval was performed with a pH 6.0 Sodium Citrate buffer.

Anti-TGF alpha antibody - ab203049 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin-embedded rat colon carcinoma tissue labeling TGF alpha with ab203049 at 1/100 dilution.

Anti-TGF alpha antibody - ab53728 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TGF alpha antibody (ab53728) at 1/500 dilutionLane 1 : extracts from COS7 cellsLane 2 : extracts from COS7 cells with immunizing peptide

Anti-TGF alpha antibody [1E8-269] - ab11456 from Abcam

Prices $359.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone 1E8-269

Anti-TGF alpha antibody [213-4.4] - ab16768 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 213-4.4
Overlay histogram showing A431 cells stained with ab16768 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab16768, 1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-TGF alpha antibody (Biotin) - ab83159 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TGF alpha antibody [P/T1] - ab9578 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone P/T1
Immunohistochemical characterization of the anti-TGF-α monoclonal antibody ab9578 on human melanoma.

Anti-TGF alpha antibody [TG86] - ab199006 from Abcam

Prices $373.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone TG86

Anti-TGF alpha antibody [TG86 + P/T1] - ab199400 from Abcam

Prices $359.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone TG86 + P/T1

Anti-TGFA / TGF Alpha Antibody - LS-C335090 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of HeLa cell lysate using TGFA antibody.

Anti-TGFA / TGF Alpha Antibody (Biotin) - LS-C211994 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of transforming growth factor alpha antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 18 kDa. Observed band size: 30 kDa Additional bands at: 35 kDa. We are unsure as to the identity of this extra band.

Anti-TGFA / TGF Alpha Antibody (FITC) - LS-C211993 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of transforming growth factor alpha antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 18 kDa. Observed band size: 30 kDa Additional bands at: 35 kDa. We are unsure as to the identity of this extra band.

Anti-TGFA / TGF Alpha Antibody (HRP) - LS-C211992 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of transforming growth factor alpha antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 18 kDa. Observed band size: 30 kDa Additional bands at: 35 kDa. We are unsure as to the identity of this extra band.

Anti-TGFA / TGF Alpha Antibody - LS-C10844 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TGFA / TGF Alpha Antibody (C-Terminus) - LS-C39821 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TGFA / TGF Alpha Antibody (C-Terminus) - LS-C39822 from LifeSpan Bioscience

Prices $635.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-TGFA / TGF Alpha Antibody - LS-C10851 from LifeSpan Bioscience

Prices $560.00
Sizes 500 µg
Host Goat
Clonality Polyclonal

Anti-TGFA / TGF Alpha Antibody (C-Terminus) - LS-C39823 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TGFA / TGF Alpha Antibody (C-Terminus) - LS-C39824 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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