Gene Symbol | CELA3B |
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Entrez Gene | 23436 |
Alt Symbol | CBPP, E1, EL-1, ELA3B |
Species | Human |
Gene Type | protein-coding |
Description | chymotrypsin-like elastase family, member 3B |
Other Description | cholesterol-binding pancreatic protease|chymotrypsin-like elastase family member 3B|elastase 1|elastase 3B, pancreatic|elastase IIIB|elastase-3B|fecal elastase 1|pancreatic elastase 1|pancreatic endopeptidase E|protease E|proteinase E |
Swissprots | P11423 Q5VU30 Q5VU28 P08861 Q5VU29 B2RE44 |
Accessions | EAW94998 EAW94999 P08861 AK092382 AK315798 BAG38141 BC005216 AAH05216 BI760781 BX497562 BX499439 M16630 AAA36482 M18692 AAA58454 XM_011541132 XP_011539434 XM_011541133 XP_011539435 XM_011541134 XP_011539436 XR_946598 NM_007352 NP_031378 |
Function | Efficient protease with alanine specificity but only little elastolytic activity. |
Tissue Specificity | Pancreas. Not detectable in keratinocytes. {ECO:0000269|PubMed:10620133}. |
Top Pathways | Protein digestion and absorption, Pancreatic secretion |
Elastase-3B CRISPR/Cas9 KO Plasmid (h) - sc-409852 from Santa Cruz Biotechnology
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Elastase-3B HDR Plasmid (h) - sc-409852-HDR from Santa Cruz Biotechnology
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Elastase-3B Double Nickase Plasmid (h) - sc-409852-NIC from Santa Cruz Biotechnology
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Elastase-3B Double Nickase Plasmid (h2) - sc-409852-NIC-2 from Santa Cruz Biotechnology
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Elastase-3B CRISPR Activation Plasmid (h) - sc-409852-ACT from Santa Cruz Biotechnology
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Elastase-3B CRISPR Activation Plasmid (h2) - sc-409852-ACT-2 from Santa Cruz Biotechnology
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Elastase-3B Lentiviral Activation Particles (h) - sc-409852-LAC from Santa Cruz Biotechnology
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Elastase-3B Lentiviral Activation Particles (h2) - sc-409852-LAC-2 from Santa Cruz Biotechnology
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Elastase-3B siRNA (h) - sc-78850 from Santa Cruz Biotechnology
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Elastase-3B shRNA Plasmid (h) - sc-78850-SH from Santa Cruz Biotechnology
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Elastase-3B shRNA (h) Lentiviral Particles - sc-78850-V from Santa Cruz Biotechnology
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Elastase RNAi - H00023436-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN5924 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5924 from Sigma-Aldrich
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CELA3B siRNA (Human) - CRH8271 from Cohesion Biosciences
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CELA3B - MBS8213990 from MyBioSource
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shRNA set against Human CELA3B (NM_007352.2) - SHH261465 from Creative biogene
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shRNA set against Human ELA3B(NM_007352.2) - SHH030665 from Creative biogene
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CELA3B shRNA Plasmid (Human) - CHH8271 from Cohesion Biosciences
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CELA3B miRNA 3'UTR clone - MiUTR1H-03184 from Creative biogene
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