Gene Symbol | PPP3R2 |
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Entrez Gene | 5535 |
Alt Symbol | PPP3RL |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 3, regulatory subunit B, beta |
Other Description | CBLP|CNBII|calcineurin B, type II (19kDa)|calcineurin B-like protein|calcineurin BII|calcineurin subunit B type 2|protein phosphatase 2B regulatory subunit 2|protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), beta isoform (calcineurin B, type II)|protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, beta isoform (calcineurin B, type II)|protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform|protein phosphatase 3 regulatory subunit B beta isoform |
Swissprots | Q8WYJ4 Q5VTR4 Q7Z4V8 Q96LZ3 |
Accessions | CBH19417 CBH30592 EAW58961 Q96LZ3 AF085237 AAL40395 AF145026 AAP97278 AF400667 AAP57772 AK057524 BAB71521 BC030595 AAH30595 BC066299 AAH66299 JF432717 ADZ15934 NM_147180 NP_671709 |
Function | Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity). {ECO:0000250}. |
Tissue Specificity | Testis-specific. {ECO:0000269|PubMed:15865209}. |
Top Pathways | Glucagon signaling pathway, Tuberculosis, Glutamatergic synapse, Amphetamine addiction, Oxytocin signaling pathway |
PP2B-B2 CRISPR/Cas9 KO Plasmid (h) - sc-408765 from Santa Cruz Biotechnology
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PP2B-B2 HDR Plasmid (h) - sc-408765-HDR from Santa Cruz Biotechnology
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PP2B-B2 Double Nickase Plasmid (h) - sc-408765-NIC from Santa Cruz Biotechnology
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PP2B-B2 Double Nickase Plasmid (h2) - sc-408765-NIC-2 from Santa Cruz Biotechnology
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PP2B-B2 CRISPR Activation Plasmid (h) - sc-408765-ACT from Santa Cruz Biotechnology
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PP2B-B2 CRISPR Activation Plasmid (h2) - sc-408765-ACT-2 from Santa Cruz Biotechnology
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PP2B-B2 Lentiviral Activation Particles (h) - sc-408765-LAC from Santa Cruz Biotechnology
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PP2B-B2 Lentiviral Activation Particles (h2) - sc-408765-LAC-2 from Santa Cruz Biotechnology
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PP2B-B2 siRNA (h) - sc-92568 from Santa Cruz Biotechnology
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PP2B-B2 shRNA Plasmid (h) - sc-92568-SH from Santa Cruz Biotechnology
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PP2B-B2 shRNA (h) Lentiviral Particles - sc-92568-V from Santa Cruz Biotechnology
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PPP3R2 RNAi - H00005535-R01 from Novus Biologicals
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MISSION® esiRNA - EHU007391 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0663 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0661 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0662 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17308 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17308 from Sigma-Aldrich
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PPP3R2 siRNA (Human) - CRH3714 from Cohesion Biosciences
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shRNA set against Human PPP3R2 (NM_147180.2) - SHH381580 from Creative biogene
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shRNA set against Human PPP3R2(NM_147180.2) - SHR135528 from Creative biogene
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PPP3R2 shRNA Plasmid (Human) - CHH3714 from Cohesion Biosciences
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PPP3R2 miRNA 3'UTR clone - MiUTR1H-08197 from Creative biogene
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