JAM2

Gene Symbol JAM2
Entrez Gene 58494
Alt Symbol C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM
Species Human
Gene Type protein-coding
Description junctional adhesion molecule 2
Other Description JAM-2|JAM-IT/VE-JAM|junctional adhesion molecule B|vascular endothelial junction-associated molecule
Swissprots Q6UXG6 Q6YNC1 B4DGT9 B2R6T9 P57087
Accessions EAX09976 EAX09977 EAX09978 P57087 AF255910 AAF81223 AI742752 AK056079 AK294769 BAG57900 AK312708 BAG35586 AM392801 CAL37679 AM392870 CAL37748 AM393811 CAL38686 AX772824 CAE06261 AY016009 AAG49022 AY077698 AAL82538 AY358361 AAQ88727 BC017779 AAH17779 BG540412 BM804795 BM921497 CX870550 XR_937537 NM_001270408 NP_001257337 NM_021219 NP_067042 NR_072999 NM_001270407 NP_001257336
Function May play a role in the processes of lymphocyte homing to secondary lymphoid organs.
Subcellular Location Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Localized at tight junctions of both epithelial and endothelial cells. {ECO:0000250}.
Tissue Specificity Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells. {ECO:0000269|PubMed:10779521}.
Top Pathways Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection

JAM-B CRISPR/Cas9 KO Plasmid (h) - sc-416708 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JAM-B HDR Plasmid (h) - sc-416708-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JAM-B Double Nickase Plasmid (h) - sc-416708-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JAM-B Double Nickase Plasmid (h2) - sc-416708-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JAM-B CRISPR Activation Plasmid (h) - sc-416708-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JAM-B CRISPR Activation Plasmid (h2) - sc-416708-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JAM-B Lentiviral Activation Particles (h) - sc-416708-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JAM-B Lentiviral Activation Particles (h2) - sc-416708-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JAM-B siRNA (h) - sc-43141 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JAM-B shRNA Plasmid (h) - sc-43141-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JAM-B shRNA (h) Lentiviral Particles - sc-43141-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JAM-B/VE-JAM RNAi - H00058494-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU015521 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10859 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10859 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01900 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01900

JAM2 siRNA (Human) - CRJ1724 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

JAM2, siRNA - MBS8214324 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human JAM2 (NM_021219.3) - SHH321983 from Creative biogene

Category siRNA
Species Reactivities Human

JAM2 shRNA Plasmid (Human) - CHJ1724 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

JAM2 miRNA 3'UTR clone - MiUTR3H-08788 from Creative biogene

Species Reactivities Human
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