Gene Symbol | ATL2 |
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Entrez Gene | 64225 |
Alt Symbol | ARL3IP2, ARL6IP2, atlastin2 |
Species | Human |
Gene Type | protein-coding |
Description | atlastin GTPase 2 |
Other Description | ADP-ribosylation factor-like 6 interacting protein 2|ADP-ribosylation factor-like protein 6-interacting protein 2|ADP-ribosylation-like factor 6 interacting protein 2|ARL-6-interacting protein 2|aip-2|atlastin-2 |
Swissprots | Q9H5M7 Q8NHH9 B7Z7X8 Q7Z630 Q4ZG30 Q8NHH8 B7Z1X2 |
Accessions | AAM97341 AAM97342 AAX88950 EAX00375 EAX00376 EAX00377 Q8NHH9 AI630457 AK026946 BAB15598 AK124434 AK225190 AK294049 BAH11658 AK294711 BAH11856 AK302621 BAH13764 AK303985 BAH14091 AK308894 AK316179 BAH14550 BC039050 BC053508 AAH53508 BX507348 DA643528 XM_006712071 XP_006712134 XM_006712072 XP_006712135 XM_011533017 XP_011531319 XM_011533018 XP_011531320 XM_011533019 XP_011531321 XM_011533020 XP_011531322 XM_011533021 XP_011531323 XM_011533022 XP_011531324 XM_011533023 XP_011531325 NM_001135673 NP_001129145 NM_001308076 NP_001295005 NM_022374 NP_071769 NR_024191 |
Function | GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. {ECO:0000269|PubMed:18270207, ECO:0000269|PubMed:19665976}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18270207}; Multi-pass membrane protein {ECO:0000269|PubMed:18270207}. |
Tissue Specificity | Expressed in peripheral tissues (at protein level). {ECO:0000269|PubMed:18270207}. |
Atlastin-2 CRISPR/Cas9 KO Plasmid (h) - sc-408272 from Santa Cruz Biotechnology
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Atlastin-2 HDR Plasmid (h) - sc-408272-HDR from Santa Cruz Biotechnology
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Atlastin-2 Double Nickase Plasmid (h) - sc-408272-NIC from Santa Cruz Biotechnology
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Atlastin-2 Double Nickase Plasmid (h2) - sc-408272-NIC-2 from Santa Cruz Biotechnology
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Atlastin-2 CRISPR Activation Plasmid (h) - sc-408272-ACT from Santa Cruz Biotechnology
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Atlastin-2 CRISPR Activation Plasmid (h2) - sc-408272-ACT-2 from Santa Cruz Biotechnology
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Atlastin-2 Lentiviral Activation Particles (h) - sc-408272-LAC from Santa Cruz Biotechnology
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Atlastin-2 Lentiviral Activation Particles (h2) - sc-408272-LAC-2 from Santa Cruz Biotechnology
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Atlastin-2 siRNA (h) - sc-94368 from Santa Cruz Biotechnology
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Atlastin-2 shRNA Plasmid (h) - sc-94368-SH from Santa Cruz Biotechnology
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Atlastin-2 shRNA (h) Lentiviral Particles - sc-94368-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU121571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3661 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04954 from Sigma-Aldrich
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ATL2 siRNA (Human) - CRJ1969 from Cohesion Biosciences
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ATL2 - MBS8230585 from MyBioSource
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shRNA set against Human ATL2 (NM_022374.2) - SHH242258 from Creative biogene
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shRNA set against Human ARL6IP2(NM_022374.2) - SHG072929 from Creative biogene
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Human ATL2 siRNA - orb272470 from Biorbyt
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ATL2 shRNA Plasmid (Human) - CHJ1969 from Cohesion Biosciences
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ATL2 miRNA 3'UTR clone - MiUTR1H-00573 from Creative biogene
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ATL2 miRNA 3'UTR clone - MiUTR3H-10564 from Creative biogene
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