ERCC4

Gene Symbol ERCC4
Entrez Gene 2072
Alt Symbol ERCC11, FANCQ, RAD1, XPF
Species Human
Gene Type protein-coding
Description excision repair cross-complementation group 4
Other Description DNA excision repair protein ERCC-4|DNA repair endonuclease XPF|DNA repair protein complementing XP-F cells|excision repair cross-complementing rodent repair deficiency, complementation group 4|excision-repair, complementing defective, in Chinese hamster|xeroderma pigmentosum group F-complementing protein|xeroderma pigmentosum, complementation group F
Swissprots Q8TD83 A5PKV6 Q92889 O00140 A8K111
Accessions AAB50174 AAL91593 EAW85117 EAW85118 Q92889 AI470593 AK289726 BAF82415 AK301930 BAG63350 AK308341 BC020741 AAH20741 BC142631 AAI42632 BC160102 AAI60102 U64315 AAB07689 XM_011522424 XP_011520726 XM_011522425 XP_011520727 XM_011522426 XP_011520728 XM_011522427 XP_011520729 XR_932805 NM_005236 NP_005227
Function Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link. {ECO:0000269|PubMed:19596235}.
Subcellular Location Nucleus {ECO:0000305}.
Top Pathways Nucleotide excision repair, Fanconi anemia pathway

XPF (D3G8C) Rabbit mAb - 13465 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3G8C
Western blot analysis of extracts from various cell lines using XPF (D3G8C) Rabbit mAb (upper) and α-Actinin (D6F6) XP ® Rabbit mAb #6487 (lower).

XPF (F-11) - sc-398032 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
XPF (F-11): sc-398032. Western blot analysis of XPF expression in KNRK whole cell lysate (A) and HeLa (B) and KNRK (C) nuclear extracts.

XPF (26) - sc-136401 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
XPF (26): sc-136401. Western blot analysis of XPF expression in HeLa whole cell lysate.

XPF (3F2/3) - sc-136153 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
XPF (3F2/3): sc-136153. Western blot analysis of XPF expression in non-transfected: sc-110760 (A) and human DcR2 transfected: sc-171209 (B) 293 whole cell lysates and HeLa (C) and MCF7 (D) nuclear extracts.

XPF (M-16) - sc-10164 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
XPF (M-16): sc-10164. Western blot analysis of XPF expression in HeLa (A) and KNRK (B) nuclear extracts.

XPF (N-15) - sc-10159 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
XPF (N-15): sc-10159. Western blot analysis of XPF expression in HeLa (A), KNRK (B), MCF7 (C) and K-562 (D) nuclear extracts and HeLa whole cell lysate (E).

XPF (H-300) - sc-28718 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
XPF (H-300): sc-28718. Western blot analysis of XPF expression in mouse testis tissue extract.

Anti-XPF antibody - ab76948 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling XPF with ab76948 at 1/200 (1µg/ml). Detection: DAB.

Anti-XPF antibody - ab73720 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-XPF antibody (ab73720) at 1/500 dilutionLane 1 : Extracts from 293 cellsLane 2 : Extracts from 293 cells with immunizing peptide at 5 µgLysates/proteins at 15 µg per lane.

Anti-XPF antibody - ab84540 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84540 at 1/500 dilution staining XPF in human prostate carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

Anti-XPF antibody [3F2/3] - ab85140 from Abcam

Prices $387.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3F2/3
IHC image of ab85140 staining in human tonsil formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab85140, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-XPF antibody [3F2/3] (FITC) - ab187798 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3F2/3

Anti-XPF antibody [3F2/3] (HRP) - ab187797 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3F2/3

Anti-XPF antibody [51] - ab3299 from Abcam

Host Mouse
Clonality Monoclonal
Clone 51

Anti-XPF antibody [SPM228] - ab17798 from Abcam

Prices $400.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone SPM228
ab17798 staining XPF (green) in Human primary fibroblasts by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with 0.2% Triton X-100 and blocked with 2% BSA for 1 hour at room temperature. Samples were incubated with primary antibody (1/300 in PBS) for 14 hours at 4°C. An Alexa Fluor® 488-conjugated Goat anti-mouse IgG polyclonal (1/300) was used as the secondary antibody. Blue - nuclei (DAPI).See Abreview

Anti-XPF antibody [SPM228], prediluted - ab54232 from Abcam

Host Mouse
Clonality Monoclonal
Clone SPM228
Immunohistochemical analysis of paraffin embedded human tonsil tissue using ab54232. Tissue sections were boiled in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

Anti-ERCC4 / XPF Antibody - LS-C18573 from LifeSpan Bioscience

Prices $455.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal

Anti-ERCC4 / XPF Antibody - LS-C42216 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ERCC4 / XPF Antibody (aa855-905) - LS-C65569 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-ERCC4 / XPF Antibody (clone 219, Azide-free) - LS-C87736 from LifeSpan Bioscience

Prices $610.00, $1,015.00
Sizes 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone 219
Formalin-fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and AEC chromogen. Note nuclear staining of lymphoid cells.

Anti-ERCC4 / XPF Antibody (clone 2C2) - LS-C173204 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2C2
Anti-ERCC4 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ERCC4.

Anti-ERCC4 / XPF Antibody (aa855-905) - LS-C288124 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human XPF/ERCC4 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-XPF/ERCC4 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-ERCC4 / XPF Antibody (clone 2A1) - LS-C173189 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A1
Anti-ERCC4 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ERCC4.

Anti-ERCC4 / XPF Antibody (clone 3H10) - LS-C173196 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H10
Anti-ERCC4 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ERCC4.

Anti-ERCC4 / XPF Antibody (clone 51, Azide-free) - LS-C87738 from LifeSpan Bioscience

Prices $610.00, $1,015.00
Sizes 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone 51
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