Gene Symbol | APBA1 |
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Entrez Gene | 320 |
Alt Symbol | D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA |
Species | Human |
Gene Type | protein-coding |
Description | amyloid beta (A4) precursor protein-binding, family A, member 1 |
Other Description | adapter protein X11alpha|adaptor protein X11alpha|amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)|amyloid beta A4 precursor protein-binding family A member 1|mint-1|neuron-specific X11 protein|neuronal munc18-1-interacting protein 1|phosphotyrosine-binding/-interacting domain (PTB)-bearing protein |
Swissprots | Q02410 O14914 Q5VYR8 O60570 |
Accessions | EAW62486 EAW62487 Q02410 AF029106 AAC05304 AF047347 AAC39766 AL713639 BC156047 AAI56048 BC157030 AAI57031 BF435835 BQ269294 DA179202 DA313538 L04953 AAA61307 XM_005251968 XP_005252025 XM_006717093 XP_006717156 XM_011518617 XP_011516919 NM_001163 NP_001154 |
Function | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20531236}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:20531236}. Nucleus {ECO:0000269|PubMed:20531236}. Note=Only about 5% of the protein is located in the nucleus. |
Tissue Specificity | Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen. {ECO:0000269|PubMed:23737971}. |
X11α (A-12) - sc-137022 from Santa Cruz Biotechnology
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X11α (B-12) - sc-137024 from Santa Cruz Biotechnology
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X11α (C-2) - sc-137023 from Santa Cruz Biotechnology
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X11α (D-20) - sc-18332 from Santa Cruz Biotechnology
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X11α (H-265) - sc-14032 from Santa Cruz Biotechnology
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Anti-APBA1 antibody - ab104477 from Abcam
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Anti-APBA1 antibody - ab3448 from Abcam
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Anti-APBA1 antibody - ab69991 from Abcam
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Anti-APBA1 antibody - ab77355 from Abcam
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Anti-APBA1 antibody - ab71571 from Abcam
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Anti-APBA1 antibody - ab93601 from Abcam
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Anti-APBA1 antibody [EPR15941] - N-terminal - ab190359 from Abcam
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Anti-APBA1 / MINT1 Antibody (N-Terminus) - LS-C144824 from LifeSpan Bioscience
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Anti-APBA1 / MINT1 Antibody (aa41-90) - LS-C40544 from LifeSpan Bioscience
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Anti-APBA1 / MINT1 Antibody - LS-C136875 from LifeSpan Bioscience
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Anti-APBA1 / MINT1 Antibody (aa573-586) - LS-C54514 from LifeSpan Bioscience
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Anti-APBA1 / MINT1 Antibody (Internal) - LS-C137050 from LifeSpan Bioscience
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Anti-APBA1 / MINT1 Antibody (Internal) IHC-plus⢠- LS-B4979 from LifeSpan Bioscience
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Anti-APBA1 / MINT1 Antibody IHC-plus⢠- LS-B7830 from LifeSpan Bioscience
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LIN10 Antibody - NBP1-88454 from Novus Biologicals
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LIN10 Antibody - NBP1-88453 from Novus Biologicals
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APBA1 Antibody - NBP1-84306 from Novus Biologicals
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APBA1 Antibody - NBP1-46422 from Novus Biologicals
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APBA1 Antibody - NBP1-06015 from Novus Biologicals
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APBA1 Antibody - NBP2-41182 from Novus Biologicals
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