| Gene Symbol |
CALM3
|
| Entrez Gene |
808
|
| Alt Symbol |
HEL-S-72, PHKD, PHKD3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
calmodulin 3 (phosphorylase kinase, delta)
|
| Other Description |
caM|calmodulin|epididymis secretory protein Li 72|prepro-calmodulin 3
|
| Swissprots |
Q13942 P62158 Q96HK3 Q53S29
|
| Accessions |
CAA36839 CAE93898 EAW57425 EAW57426 EAW57427 EAW57428 EAW57429 AK094964 AK295927 BAG58713 AK310762 AL050207 AW883334 BC005137 AAH05137 BC006182 AAH06182 BG753029 BT006855 AAP35501 FJ224310 ACI46002 J04046 AAA51918 NM_005184 NP_005175
|
| Function |
Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. {ECO:0000269|PubMed:16760425, ECO:0000269|PubMed:23893133}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:16760425}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:16760425}. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
|
| Top Pathways |
Estrogen signaling pathway, Rap1 signaling pathway, Alcoholism, cAMP signaling pathway, Circadian entrainment
|