Cyp2e1
| Gene Symbol | Cyp2e1 |
|---|---|
| Entrez Gene | 13106 |
| Alt Symbol | Cyp2e |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | cytochrome P450, family 2, subfamily e, polypeptide 1 |
| Other Description | 4-nitrophenol 2-hydroxylase|CYPIIE1|cytochrome P450 2E1|cytochrome P450, 2e1, ethanol inducible|cytochrome P450-ALC|cytochrome P450-J |
| Swissprots | Q9Z198 Q05421 |
| Accessions | EDL17941 EDL17942 EDL17943 EDL17944 EDL17945 EDL17946 Q05421 BC013451 AAH13451 BC042693 DQ838976 ABH07947 DQ838977 ABH07948 L11650 AAA39879 M27582 M54877 AAA37275 X01026 CAA25510 X62595 CAA44481 NM_021282 NP_067257 |
| Function | Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. {ECO:0000250}. |
| Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Tissue Specificity | Highest level in the liver and to a lesser extent in the kidney, with a higher level in the male kidney than in the female. |
| Top Pathways | Steroid hormone biosynthesis, Chemical carcinogenesis, Non-alcoholic fatty liver disease (NAFLD), Arachidonic acid metabolism, Linoleic acid metabolism |
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