Gene Symbol | FCGR2A |
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Entrez Gene | 2212 |
Alt Symbol | CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2 |
Species | Human |
Gene Type | protein-coding |
Description | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
Other Description | Immunoglobulin G Fc receptor II|fc-gamma RII-a|fc-gamma-RIIa|fcRII-a|igG Fc receptor II-a|low affinity immunoglobulin gamma Fc region receptor II-a |
Swissprots | Q8WW64 P12318 Q8WUN1 |
Accessions | AAL99539 ABK41920 CAA01563 CAA48217 P12318 AF416711 AAL78867 AI250177 AK225438 AK225601 AK226059 AK298657 BAH12840 AK298734 BAH12860 AK315225 BAG37654 BC019931 AAH19931 BC020823 AAH20823 DQ892037 ABM82963 DQ895228 ABM86154 J03619 AAA35932 M28697 AAA36050 M31932 AAA35827 X62572 Y00644 CAA68672 XM_011509287 XP_011507589 XM_011509288 XP_011507590 XM_011509289 XP_011507591 XM_011509290 XP_011507592 XM_011509291 XP_011507593 NM_001136219 NP_001129691 NM_021642 NP_067674 |
Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. {ECO:0000269|PubMed:19011614}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:19011614}; Single-pass type I membrane protein {ECO:0000269|PubMed:19011614}. |
Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
Top Pathways | Systemic lupus erythematosus, Fc gamma R-mediated phagocytosis, Leishmaniasis, Phagosome, Staphylococcus aureus infection |
Active human CD32A protein fragment - ab173994 from Abcam
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Human CD32 protein fragment - ab139784 from Abcam
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Human CD32 protein fragment - ab151359 from Abcam
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CD32A Antibody Blocking Peptide - LS-E2650 from LifeSpan Bioscience
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CD32A Antibody Blocking Peptide - LS-E9853 from LifeSpan Bioscience
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Fc gamma RIIA/CD32a Partial Recombinant Protein - H00002212-Q01 from Novus Biologicals
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Recombinant Human Fc gamma RIIA/CD32a Protein - NBP2-23045 from Novus Biologicals
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Fc gamma RIIA/CD32a Recombinant Protein - H00002212-G01 from Novus Biologicals
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Fc gamma RIIA/CD32a Recombinant Protein - P3684 from Novus Biologicals
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FCGR2A-Antibody-C-term-Blocking-peptide - BP13724b from Abgent, a WuXi AppTec company
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FCGR2A-Antibody-C-term-Blocking-Peptide - BP8918b from Abgent, a WuXi AppTec company
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Recombinant Human Fc gamma RIIA/CD32a (R167) - 1330-CD-050 from R&D Systems
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Recombinant Human Fc gamma RIIA/CD32a (R167), CF - 1330-CD-050/CF from R&D Systems
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Human CD32a protein - orb49380 from Biorbyt
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Human CD32a protein (His Tag) - orb138408 from Biorbyt
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Human CD32a protein (His Tag) - orb138407 from Biorbyt
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FCGR2A protein (His tag) - 80R-2640 from Fitzgerald
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Human FcgRII Protein - abx068832 from Abbexa
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CD32 / FcRII-a (34-216, His-tag) - AR50760PU-N from Acris Antibodies
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CD32 / FcRII-a (34-216, His-tag) - AR50760PU-S from Acris Antibodies
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CD32 / FcRII-a - H00002212-G01 from Acris Antibodies
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CD32 / FcRII-a - H00002212-Q01-10 from Acris Antibodies
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CD32 / FcRII-a - H00002212-Q01-25 from Acris Antibodies
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CD32 / FcRII-a - H00002213-Q01-10 from Acris Antibodies
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CD32 / FcRII-a - H00002213-Q01-25 from Acris Antibodies
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