Gene Symbol | GCLC |
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Entrez Gene | 2729 |
Alt Symbol | GCL, GCS, GLCL, GLCLC |
Species | Human |
Gene Type | protein-coding |
Description | glutamate-cysteine ligase, catalytic subunit |
Other Description | GCS heavy chain|gamma-ECS|gamma-glutamylcysteine synthetase|glutamate--cysteine ligase catalytic subunit |
Swissprots | P48506 Q14399 |
Accessions | AAC41751 AAD18031 AAR29974 AAV31778 EAX04425 EAX04426 P48506 AB262176 BAE97618 AB516284 BAJ21361 AK094940 AK304288 BAG65146 AK313480 BAG36264 AL531593 BC022487 AAH22487 BC039894 AAH39894 BC047788 BG700922 BG704750 BI550814 EU832317 ACE87574 EU832402 ACE86887 M90656 AAA58499 NM_001197115 NP_001184044 NM_001498 NP_001489 |
Top Pathways | Glutathione metabolism |
γ-GCSc CRISPR/Cas9 KO Plasmid (h) - sc-401133 from Santa Cruz Biotechnology
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γ-GCSc HDR Plasmid (h) - sc-401133-HDR from Santa Cruz Biotechnology
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γ-GCSc Double Nickase Plasmid (h) - sc-401133-NIC from Santa Cruz Biotechnology
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γ-GCSc Double Nickase Plasmid (h2) - sc-401133-NIC-2 from Santa Cruz Biotechnology
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γ-GCSc CRISPR Activation Plasmid (h) - sc-401133-ACT from Santa Cruz Biotechnology
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γ-GCSc CRISPR Activation Plasmid (h2) - sc-401133-ACT-2 from Santa Cruz Biotechnology
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γ-GCSc Lentiviral Activation Particles (h) - sc-401133-LAC from Santa Cruz Biotechnology
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γ-GCSc Lentiviral Activation Particles (h2) - sc-401133-LAC-2 from Santa Cruz Biotechnology
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γ-GCSc siRNA (h) - sc-41978 from Santa Cruz Biotechnology
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γ-GCSc shRNA Plasmid (h) - sc-41978-SH from Santa Cruz Biotechnology
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γ-GCSc shRNA (h) Lentiviral Particles - sc-41978-V from Santa Cruz Biotechnology
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GCLC RNAi - H00002729-R01 from Novus Biologicals
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MISSION® esiRNA - EHU048791 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9191 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09219 from Sigma-Aldrich
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GCLC siRNA (Human) - CRH1814 from Cohesion Biosciences
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GCLC - MBS8205191 from MyBioSource
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γ-GCSc CRISPR/Cas9 KO Plasmid (h2) - sc-401133-KO-2 from Santa Cruz Biotechnology
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γ-GCSc HDR Plasmid (h2) - sc-401133-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GCLC (NM_001498.3) - SHH300046 from Creative biogene
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Human GCLC siRNA - orb262316 from Biorbyt
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GCLC shRNA Plasmid (Human) - CHH1814 from Cohesion Biosciences
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GCLC miRNA 3'UTR clone - MiUTR3H-08778 from Creative biogene
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