| Gene Symbol | Hlcs |
|---|---|
| Entrez Gene | 110948 |
| Alt Symbol | 410I21.SP6, D16Jhu34 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) |
| Other Description | biotin apo-protein ligase|biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase|biotin--protein ligase |
| Swissprots | Q920N2 |
| Accessions | EDL03749 EDL03750 Q920N2 AB066227 BAB68213 AK052424 AK158212 BAE34407 AK164351 AK168925 BAE40738 BC037760 BC050090 AAH50090 XM_006522850 XP_006522913 XM_006522851 XP_006522914 XM_006522852 XP_006522915 XM_006522853 XP_006522916 XM_006522854 XP_006522917 XM_006522855 XP_006522918 XM_006522856 XP_006522919 XM_006523155 XP_006523218 XM_011251409 XP_011249711 NM_139145 NP_631884 |
| Function | Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl- CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Mitochondrion {ECO:0000250}. |
| Top Pathways | Biotin metabolism |