| Gene Symbol |
GTF2E1
|
| Entrez Gene |
2960
|
| Alt Symbol |
FE, TF2E1, TFIIE-A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
general transcription factor IIE, polypeptide 1, alpha 56kDa
|
| Other Description |
TFIIE-alpha|general transcription factor IIE 56 kDa subunit|general transcription factor IIE subunit 1|transcription initiation factor IIE subunit alpha
|
| Swissprots |
P29083 Q16103
|
| Accessions |
EAW79519 P29083 AK223401 BAD97121 BC005917 AAH05917 BC156224 AAI56225 BC156997 AAI56998 DA498425 S67859 AAB20413 X63468 CAA45068 XM_011512744 XP_011511046 XM_011512745 XP_011511047 NM_005513 NP_005504
|
| Function |
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
Viral carcinogenesis, Epstein-Barr virus infection, Basal transcription factors
|
![Western Blot: TFIIE-alpha Overexpression Lysate (Adult Normal) [NBP2-10463] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TFIIE-alpha.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7482_TFIIE-alpha%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10463-img0001.jpg)