| Gene Symbol | GTF2E1 |
|---|---|
| Entrez Gene | 2960 |
| Alt Symbol | FE, TF2E1, TFIIE-A |
| Species | Human |
| Gene Type | protein-coding |
| Description | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| Other Description | TFIIE-alpha|general transcription factor IIE 56 kDa subunit|general transcription factor IIE subunit 1|transcription initiation factor IIE subunit alpha |
| Swissprots | P29083 Q16103 |
| Accessions | EAW79519 P29083 AK223401 BAD97121 BC005917 AAH05917 BC156224 AAI56225 BC156997 AAI56998 DA498425 S67859 AAB20413 X63468 CAA45068 XM_011512744 XP_011511046 XM_011512745 XP_011511047 NM_005513 NP_005504 |
| Function | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. |
| Subcellular Location | Nucleus. |
| Top Pathways | Viral carcinogenesis, Epstein-Barr virus infection, Basal transcription factors |