Gene Symbol | Pign |
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Entrez Gene | 27392 |
Alt Symbol | Gm20308, PIG-N |
Species | Mouse |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class N |
Other Description | GPI ethanolamine phosphate transferase 1|phosphatidylinositol glycan, class N|phosphatidylinositol-glycan biosynthesis class N protein |
Swissprots | Q9R1S3 Q3V0S6 Q8VCC3 Q9R1S1 Q9R1S2 |
Accessions | BAA82663 EDL39874 Q9R1S3 AB030279 BAA82619 AB030280 BAA82620 AK014165 AK082387 AK132928 BAE21427 AK165971 BC021148 AAH21148 XM_006529675 XP_006529738 XM_006529676 XP_006529739 XM_006529677 XP_006529740 XM_006529678 XP_006529741 XR_387174 XR_387175 NM_013784 NP_038812 |
Function | Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. May act as suppressor of replication stress and chromosome missegregation. {ECO:0000269|PubMed:10574991}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10574991}; Multi-pass membrane protein {ECO:0000269|PubMed:10574991}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-N CRISPR/Cas9 KO Plasmid (m) - sc-424261 from Santa Cruz Biotechnology
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PIG-N HDR Plasmid (m) - sc-424261-HDR from Santa Cruz Biotechnology
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PIG-N Double Nickase Plasmid (m) - sc-424261-NIC from Santa Cruz Biotechnology
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PIG-N Double Nickase Plasmid (m2) - sc-424261-NIC-2 from Santa Cruz Biotechnology
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PIG-N CRISPR Activation Plasmid (m) - sc-424261-ACT from Santa Cruz Biotechnology
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PIG-N CRISPR Activation Plasmid (m2) - sc-424261-ACT-2 from Santa Cruz Biotechnology
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PIG-N Lentiviral Activation Particles (m) - sc-424261-LAC from Santa Cruz Biotechnology
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PIG-N Lentiviral Activation Particles (m2) - sc-424261-LAC-2 from Santa Cruz Biotechnology
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PIG-N siRNA (m) - sc-152254 from Santa Cruz Biotechnology
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PIG-N shRNA Plasmid (m) - sc-152254-SH from Santa Cruz Biotechnology
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PIG-N shRNA (m) Lentiviral Particles - sc-152254-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU017311 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN38708 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38708 from Sigma-Aldrich
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shRNA set against Mouse PIGN (NM_013784.3) - SHH375460 from Creative biogene
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