Gene Symbol | ADIPOQ |
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Entrez Gene | 282865 |
Alt Symbol | ACRP30, APM1 |
Species | Bovine |
Gene Type | protein-coding |
Description | adiponectin, C1Q and collagen domain containing |
Other Description | 30 kDa adipocyte complement-related protein|adipocyte complement related 30kDa protein|adipocyte complement related protein of 30 kDa|adipocyte complement-related 30 kDa protein|adipocyte, C1q and collagen domain-containing protein|adiponectin|adipose most abundant gene transcript 1 protein|apM-1 |
Swissprots | A5D7A8 Q95MQ4 Q3Y5Z3 |
Accessions | AAZ81421 DAA33345 Q3Y5Z3 AF269230 AAK58902 BC140488 AAI40489 XM_010801273 XP_010799575 XM_010801274 XP_010799576 XM_010822448 XP_010820750 XM_010822453 XP_010820755 NM_174742 NP_777167 |
Function | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | Adipocytokine signaling pathway, Type II diabetes mellitus, PPAR signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway |
Bovine ADIPOQ protein - orb246165 from Biorbyt
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Bovine ADIPOQ protein - orb244840 from Biorbyt
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Recombinant Adiponectin (ADP) - RPA605Bo01 from Cloud-clone
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Recombinant Bovine Adiponectin(ADIPOQ) - CSB-YP661101BO CSB-BP661101BO CSB-MP661101BO from Cusabio
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Recombinant Bovine Adiponectin(ADIPOQ) - CSB-EP661101BO from Cusabio
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Adiponectin (ADIPOQ) - MBS1366165 from MyBioSource
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Adiponectin Protein (Recombinant) - abx166289 from Abbexa
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ADIPOQ Recombinant Protein (OPCA02279) - OPCA02279 from Aviva Systems Biology
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ADIPOQ Recombinant Protein (OPCA03018) - OPCA03018 from Aviva Systems Biology
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Recombinant Adiponectin (ADP) - RPU54323 from Biomatik
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ADIPOQ Recombinant Protein (OPCD01145) - OPCD01145 from Aviva Systems Biology
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Recombinant bovine Adiponectin - AP71314 from Signalway Antibody
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Recombinant bovine Adiponectin - AP73067 from Signalway Antibody
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Recombinant Bovine Adiponectin (ADIPOQ) - RPC23090 from Biomatik
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Recombinant Bovine Adiponectin (ADIPOQ) - RPC25391 from Biomatik
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