| Gene Symbol |
Chrna2
|
| Entrez Gene |
170945
|
| Alt Symbol |
ACHR
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, nicotinic, alpha 2 (neuronal)
|
| Other Description |
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)|neuronal acetylcholine receptor subunit alpha-2|nicotinic acetylcholine receptor
|
| Swissprots |
P12389 Q53YK3 O08952
|
| Accessions |
AAA40664 EDL85379 EDL85380 P12389 AY574253 AAS90349 L10077 AAB60900 XM_008770735 XP_008768957 NM_133420 NP_596911
|
| Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
| Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|